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ORC1 (Origin Recognition Complex, Subunit 1, ORC1L)

Short Description: The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is the largest subunit of the ORC complex. While other ORC subunits are stable throughout the cell cycle, the levels of this protein vary during the cell cycle, which has been shown to be controlled by ubiquitin-mediated proteolysis after initiation of DNA replication. This protein is found to be selectively phosphorylated during mitosis. It is also reported to interact with MYST histone acetyltransferase 2 (MyST2/HBO1), a protein involved in control of transcription silencing. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].
More information related to gene ORC1.

Products related to ORC1 Gene:

60 results :

Human ORC1L ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Origin Recognition Complex, Subunit 1-Like (Yeast) (ORC1L)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5762362
Datasheet
Catalog No. ABIN5762362
Type:
ORF
Application:
Cloning
Gene:
Origin Recognition Complex, Subunit 1-Like (Yeast) (ORC1L)
Species:
Human
Synonyms:
Orc1, ORC1, orc1.L
Insert length:
2586 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human ORC1L cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Origin Recognition Complex, Subunit 1-Like (Yeast) (ORC1L)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4478982
Datasheet
Catalog No. ABIN4478982
Type:
cDNA
Application:
Protein Expression
Gene:
Origin Recognition Complex, Subunit 1-Like (Yeast) (ORC1L)
Species:
Human
Synonyms:
Orc1, ORC1, orc1.L
Insert length:
2586 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human ORC1L CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Origin Recognition Complex, Subunit 1-Like (Yeast) (ORC1L)
NCBI Accession:
NM_004153
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5276673
Datasheet
Catalog No. ABIN5276673
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Origin Recognition Complex, Subunit 1-Like (Yeast) (ORC1L)
NCBI Accession:
NM_004153
Species:
Human
Synonyms:
Orc1, ORC1, orc1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ORC1L
Format:
Viral Particles
Storage:
-80 °C
Rat ORC1L CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Origin Recognition Complex, Subunit 1-Like (Yeast) (ORC1L)
NCBI Accession:
NM_177931
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5276671
Datasheet
Catalog No. ABIN5276671
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Origin Recognition Complex, Subunit 1-Like (Yeast) (ORC1L)
NCBI Accession:
NM_177931
Species:
Rat
Synonyms:
Orc1, ORC1, orc1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Orc1
Format:
Viral Particles
Storage:
-80 °C
Mouse ORC1L CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Origin Recognition Complex, Subunit 1-Like (Yeast) (ORC1L)
NCBI Accession:
NM_011015
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5276669
Datasheet
Catalog No. ABIN5276669
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Origin Recognition Complex, Subunit 1-Like (Yeast) (ORC1L)
NCBI Accession:
NM_011015
Species:
Mouse
Synonyms:
Orc1, ORC1, orc1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Orc1
Format:
Viral Particles
Storage:
-80 °C
Human ORC1L CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Origin Recognition Complex, Subunit 1-Like (Yeast) (ORC1L)
NCBI Accession:
NM_001190818
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5276667
Datasheet
Catalog No. ABIN5276667
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Origin Recognition Complex, Subunit 1-Like (Yeast) (ORC1L)
NCBI Accession:
NM_001190818
Species:
Human
Synonyms:
Orc1, ORC1, orc1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ORC1
Format:
Viral Particles
Storage:
-80 °C
Human ORC1L CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Origin Recognition Complex, Subunit 1-Like (Yeast) (ORC1L)
NCBI Accession:
NM_001190818
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5161088
Datasheet
Catalog No. ABIN5161088
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Origin Recognition Complex, Subunit 1-Like (Yeast) (ORC1L)
NCBI Accession:
NM_001190818
Species:
Human
Synonyms:
Orc1, ORC1, orc1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ORC1
Format:
Viral Particles
Storage:
-80 °C
Rat ORC1L CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Origin Recognition Complex, Subunit 1-Like (Yeast) (ORC1L)
NCBI Accession:
NM_177931
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5161092
Datasheet
Catalog No. ABIN5161092
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Origin Recognition Complex, Subunit 1-Like (Yeast) (ORC1L)
NCBI Accession:
NM_177931
Species:
Rat
Synonyms:
Orc1, ORC1, orc1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Orc1
Format:
Viral Particles
Storage:
-80 °C
Mouse ORC1L CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Origin Recognition Complex, Subunit 1-Like (Yeast) (ORC1L)
NCBI Accession:
NM_011015
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5161090
Datasheet
Catalog No. ABIN5161090
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Origin Recognition Complex, Subunit 1-Like (Yeast) (ORC1L)
NCBI Accession:
NM_011015
Species:
Mouse
Synonyms:
Orc1, ORC1, orc1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Orc1
Format:
Viral Particles
Storage:
-80 °C
Human ORC1L CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Origin Recognition Complex, Subunit 1-Like (Yeast) (ORC1L)
NCBI Accession:
NM_004153
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5161086
Datasheet
Catalog No. ABIN5161086
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Origin Recognition Complex, Subunit 1-Like (Yeast) (ORC1L)
NCBI Accession:
NM_004153
Species:
Human
Synonyms:
Orc1, ORC1, orc1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ORC1L
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • DYKDDDDK Tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pPB-His-GST
    • pPB-His-MBP
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-XL5
    • pDONR223
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Retroviral Vector
    • Bacterial Expression Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • PGK Promoter
    • SFFV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to ORC1

  • Origin recognition complex subunit 1 (Orc1)
  • origin recognition complex subunit 1 (Orc1)
  • origin recognition complex subunit 1 (ORC1)
  • origin recognition complex subunit 1 L homeolog (orc1.L)
  • origin recognition complex, subunit 1 (Orc1)
  • AA545195
  • CG10667
  • Dmel\\CG10667
  • DmORC1
  • DmOrc1
  • DmOrc1p
  • dORC1
  • HSORC1
  • MmORC1
  • ORC
  • ORC1
  • orc1
  • ORC1L
  • orc1l
  • Orc1l
  • PARC1
  • rDmORC
  • xorc1

Gene-IDs for different species

Protein level used designations for ORC1

  • CG10667-PA
  • Orc1-PA
  • origin recognition complex 1
  • origin recognition complex subunit 1
  • origin recognition complex, subunit 1 homolog
  • replication control protein 1
  • origin recognition complex protein 1
  • origin recognition complex, subunit 1-like
Other products related to ORC1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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