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PCSK1 (Proprotein Convertase Subtilisin/kexin Type 1, PCSK1)

Short Description: The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. Mutations in this gene have been associated with susceptibility to obesity and proprotein convertase 1/3 deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2010].
More information related to gene PCSK1.

Products related to PCSK1 Gene:

65 results :

Human PCSK1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5756653
Datasheet
Catalog No. ABIN5756653
Type:
ORF
Application:
Cloning
Gene:
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1)
Species:
Human
Synonyms:
PCSK1, Pcsk1, pcsk1, PC1B
Insert length:
2262 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat PCSK1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1)
NCBI Accession:
NM_017091
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5265755
Datasheet
Catalog No. ABIN5265755
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1)
NCBI Accession:
NM_017091
Species:
Rat
Synonyms:
PCSK1, Pcsk1, pcsk1, PC1B
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Pcsk1
Format:
Viral Particles
Storage:
-80 °C
Mouse PCSK1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1)
NCBI Accession:
NM_013628
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5265753
Datasheet
Catalog No. ABIN5265753
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1)
NCBI Accession:
NM_013628
Species:
Mouse
Synonyms:
PCSK1, Pcsk1, pcsk1, PC1B
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Pcsk1
Format:
Viral Particles
Storage:
-80 °C
Human PCSK1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1)
NCBI Accession:
NM_000439
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5265751
Datasheet
Catalog No. ABIN5265751
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1)
NCBI Accession:
NM_000439
Species:
Human
Synonyms:
PCSK1, Pcsk1, pcsk1, PC1B
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PCSK1
Format:
Viral Particles
Storage:
-80 °C
Rat PCSK1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1)
NCBI Accession:
NM_017091
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5150205
Datasheet
Catalog No. ABIN5150205
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1)
NCBI Accession:
NM_017091
Species:
Rat
Synonyms:
PCSK1, Pcsk1, pcsk1, PC1B
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Pcsk1
Format:
Viral Particles
Storage:
-80 °C
Mouse PCSK1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1)
NCBI Accession:
NM_013628
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5150203
Datasheet
Catalog No. ABIN5150203
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1)
NCBI Accession:
NM_013628
Species:
Mouse
Synonyms:
PCSK1, Pcsk1, pcsk1, PC1B
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Pcsk1
Format:
Viral Particles
Storage:
-80 °C
Human PCSK1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1)
NCBI Accession:
NM_000439
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5150201
Datasheet
Catalog No. ABIN5150201
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1)
NCBI Accession:
NM_000439
Species:
Human
Synonyms:
PCSK1, Pcsk1, pcsk1, PC1B
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PCSK1
Format:
Viral Particles
Storage:
-80 °C
Mouse PCSK1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1)
NCBI Accession:
NM_013628
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5756654
Datasheet
Catalog No. ABIN5756654
Type:
ORF
Application:
Cloning
Gene:
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1)
NCBI Accession:
NM_013628
Species:
Mouse
Synonyms:
PCSK1, Pcsk1, pcsk1, PC1B
Insert length:
2262 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat PCSK1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1)
NCBI Accession:
NM_017091
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5756655
Datasheet
Catalog No. ABIN5756655
Type:
ORF
Application:
Cloning
Gene:
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1)
NCBI Accession:
NM_017091
Species:
Rat
Synonyms:
PCSK1, Pcsk1, pcsk1, PC1B
Insert length:
2259 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human PCSK1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4485606
Datasheet
Catalog No. ABIN4485606
Type:
cDNA
Application:
Protein Expression
Gene:
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1)
Species:
Human
Synonyms:
PCSK1, Pcsk1, pcsk1, PC1B
Insert length:
2262 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-XL4
    • pCMV6-XL5
    • pDONR223
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PCSK1

  • proprotein convertase subtilisin/kexin type 1 (PCSK1)
  • proprotein convertase subtilisin/kexin type 1 (Pcsk1)
  • proprotein convertase subtilisin/kexin type 1 (pcsk1)
  • prohormone convertase 1 (PC1B)
  • BDP
  • BMIQ12
  • Nec-1
  • NEC1
  • Nec1
  • PC1
  • PC1/3
  • PC3
  • Phpp-1
  • SPC3

Gene-IDs for different species

Protein level used designations for PCSK1

  • NEC 1
  • neuroendocrine convertase 1
  • prohormone convertase 1
  • prohormone convertase 3
  • furin homolog
  • prohormone convertase 1/3
  • propeptide-processing protease
  • proprotein convertase 1
  • Protein convertase subtilisin / kexin type I
  • Protein convertase subtilisin / kexin, type I
  • prohormone convertase
Other products related to PCSK1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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