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PEN2 (Presenilin Enhancer 2 Homolog, PSENEN)

Short Description: Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. [provided by RefSeq, Jul 2008].
More information related to gene PEN2.

Products related to PEN2 Gene:

57 results :

Human PSENEN ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Presenilin Enhancer 2 Homolog (C. Elegans) (PSENEN)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5756737
Datasheet
Catalog No. ABIN5756737
Type:
ORF
Application:
Cloning
Gene:
Presenilin Enhancer 2 Homolog (C. Elegans) (PSENEN)
Species:
Human
Synonyms:
PSENEN, PEN2, Psenen, pen-2, psenen.S, psenen
Insert length:
306 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human PSENEN cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Presenilin Enhancer 2 Homolog (C. Elegans) (PSENEN)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4479872
Datasheet
Catalog No. ABIN4479872
Type:
cDNA
Application:
Protein Expression
Gene:
Presenilin Enhancer 2 Homolog (C. Elegans) (PSENEN)
Species:
Human
Synonyms:
PSENEN, PEN2, Psenen, pen-2, psenen.S, psenen
Insert length:
306 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse PSENEN CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Presenilin Enhancer 2 Homolog (C. Elegans) (PSENEN)
NCBI Accession:
NM_025498
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5265873
Datasheet
Catalog No. ABIN5265873
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Presenilin Enhancer 2 Homolog (C. Elegans) (PSENEN)
NCBI Accession:
NM_025498
Species:
Mouse
Synonyms:
PSENEN, PEN2, Psenen, pen-2, psenen.S, psenen
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Psenen
Format:
Viral Particles
Storage:
-80 °C
Human PSENEN CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Presenilin Enhancer 2 Homolog (C. Elegans) (PSENEN)
NCBI Accession:
NM_172341
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5265871
Datasheet
Catalog No. ABIN5265871
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Presenilin Enhancer 2 Homolog (C. Elegans) (PSENEN)
NCBI Accession:
NM_172341
Species:
Human
Synonyms:
PSENEN, PEN2, Psenen, pen-2, psenen.S, psenen
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PSENEN
Format:
Viral Particles
Storage:
-80 °C
Rat PSENEN CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Presenilin Enhancer 2 Homolog (C. Elegans) (PSENEN)
NCBI Accession:
NM_001008764
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5265875
Datasheet
Catalog No. ABIN5265875
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Presenilin Enhancer 2 Homolog (C. Elegans) (PSENEN)
NCBI Accession:
NM_001008764
Species:
Rat
Synonyms:
PSENEN, PEN2, Psenen, pen-2, psenen.S, psenen
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Psenen
Format:
Viral Particles
Storage:
-80 °C
Mouse PSENEN CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Presenilin Enhancer 2 Homolog (C. Elegans) (PSENEN)
NCBI Accession:
NM_025498
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5150323
Datasheet
Catalog No. ABIN5150323
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Presenilin Enhancer 2 Homolog (C. Elegans) (PSENEN)
NCBI Accession:
NM_025498
Species:
Mouse
Synonyms:
PSENEN, PEN2, Psenen, pen-2, psenen.S, psenen
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Psenen
Format:
Viral Particles
Storage:
-80 °C
Rat PSENEN CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Presenilin Enhancer 2 Homolog (C. Elegans) (PSENEN)
NCBI Accession:
NM_001008764
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5150325
Datasheet
Catalog No. ABIN5150325
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Presenilin Enhancer 2 Homolog (C. Elegans) (PSENEN)
NCBI Accession:
NM_001008764
Species:
Rat
Synonyms:
PSENEN, PEN2, Psenen, pen-2, psenen.S, psenen
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Psenen
Format:
Viral Particles
Storage:
-80 °C
Human PSENEN CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Presenilin Enhancer 2 Homolog (C. Elegans) (PSENEN)
NCBI Accession:
NM_172341
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5150321
Datasheet
Catalog No. ABIN5150321
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Presenilin Enhancer 2 Homolog (C. Elegans) (PSENEN)
NCBI Accession:
NM_172341
Species:
Human
Synonyms:
PSENEN, PEN2, Psenen, pen-2, psenen.S, psenen
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PSENEN
Format:
Viral Particles
Storage:
-80 °C
Human PSENEN cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Presenilin Enhancer 2 Homolog (C. Elegans) (PSENEN)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4838287
Datasheet
Catalog No. ABIN4838287
Type:
cDNA
Application:
Cloning
Gene:
Presenilin Enhancer 2 Homolog (C. Elegans) (PSENEN)
Species:
Human
Synonyms:
PSENEN, PEN2, Psenen, pen-2, psenen.S, psenen
Insert length:
306 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human PSENEN cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Presenilin Enhancer 2 Homolog (C. Elegans) (PSENEN)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4623343
Datasheet
Catalog No. ABIN4623343
Type:
cDNA
Application:
Cloning
Gene:
Presenilin Enhancer 2 Homolog (C. Elegans) (PSENEN)
Species:
Human
Synonyms:
PSENEN, PEN2, Psenen, pen-2, psenen.S, psenen
Insert length:
306 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pCMV6-AC
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pDONR223
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PEN2

  • presenilin enhancer gamma-secretase subunit (PSENEN)
  • presenilin enhancer 2 (PEN2)
  • presenilin enhancer 2 (Psenen)
  • presenilin enhancer gamma secretase subunit (Psenen)
  • Gamma-secretase subunit pen-2 (pen-2)
  • presenilin enhancer (pen-2)
  • presenilin enhancer gamma secretase subunit S homeolog (psenen.S)
  • presenilin enhancer gamma secretase subunit (psenen)
  • presenilin enhancer gamma-secretase subunit (Psenen)
  • 1700023M09Rik
  • ACYPI006208
  • anon-AE003800.1
  • CG33198
  • Dmel\\CG33198
  • dPen-2
  • MSTP064
  • PEN-2
  • Pen-2
  • pen-2
  • PEN2
  • pen2
  • Psenen
  • psenen
  • RGD1312037
  • zgc:109727

Gene-IDs for different species

Protein level used designations for PEN2

  • gamma-secretase subunit PEN-2
  • hematopoietic stem/progenitor cells protein MDS033
  • presenilin enhancer protein 2
  • presenilin enhancer 2
  • LRRGT00140 mRNA
  • liver regeneration-related protein LRRGT00140
  • CG33198-PA
  • pen-2-PA
  • presenilin enhancer 2 homolog
  • presenilin enhancer gamma secretase subunit S homeolog
  • Presenilin enhancer protein 2 homolog
  • presenilin enhancer protein 2 homolog
Other products related to PEN2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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