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PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1, PFKFB1)

Short Description: This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012].
More information related to gene PFKFB1.

Products related to PFKFB1 Gene:

67 results :

Human PFKFB1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5737571
Datasheet
Catalog No. ABIN5737571
Type:
ORF
Application:
Cloning
Gene:
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1)
Species:
Human
Synonyms:
pfkfb1, PFKFB1, pfkfb1.S, LOC100475853, Pfkfb1
Insert length:
1416 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat PFKFB1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1)
NCBI Accession:
NM_012621
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5113174
Datasheet
Catalog No. ABIN5113174
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1)
NCBI Accession:
NM_012621
Species:
Rat
Synonyms:
pfkfb1, PFKFB1, pfkfb1.S, LOC100475853, Pfkfb1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Pfkfb1
Format:
Viral Particles
Storage:
-80 °C
Mouse PFKFB1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1)
NCBI Accession:
NM_008824
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5113172
Datasheet
Catalog No. ABIN5113172
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1)
NCBI Accession:
NM_008824
Species:
Mouse
Synonyms:
pfkfb1, PFKFB1, pfkfb1.S, LOC100475853, Pfkfb1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Pfkfb1
Format:
Viral Particles
Storage:
-80 °C
Human PFKFB1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1)
NCBI Accession:
NM_002625
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5113170
Datasheet
Catalog No. ABIN5113170
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1)
NCBI Accession:
NM_002625
Species:
Human
Synonyms:
pfkfb1, PFKFB1, pfkfb1.S, LOC100475853, Pfkfb1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PFKFB1
Format:
Viral Particles
Storage:
-80 °C
Mouse PFKFB1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1)
NCBI Accession:
NM_008824
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5737572
Datasheet
Catalog No. ABIN5737572
Type:
ORF
Application:
Cloning
Gene:
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1)
NCBI Accession:
NM_008824
Species:
Mouse
Synonyms:
pfkfb1, PFKFB1, pfkfb1.S, LOC100475853, Pfkfb1
Insert length:
1347 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat PFKFB1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1)
NCBI Accession:
NM_012621
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5737573
Datasheet
Catalog No. ABIN5737573
Type:
ORF
Application:
Cloning
Gene:
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1)
NCBI Accession:
NM_012621
Species:
Rat
Synonyms:
pfkfb1, PFKFB1, pfkfb1.S, LOC100475853, Pfkfb1
Insert length:
1416 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat PFKFB1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1)
NCBI Accession:
NM_012621
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5228504
Datasheet
Catalog No. ABIN5228504
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1)
NCBI Accession:
NM_012621
Species:
Rat
Synonyms:
pfkfb1, PFKFB1, pfkfb1.S, LOC100475853, Pfkfb1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Pfkfb1
Format:
Viral Particles
Storage:
-80 °C
Mouse PFKFB1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1)
NCBI Accession:
NM_008824
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5228502
Datasheet
Catalog No. ABIN5228502
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1)
NCBI Accession:
NM_008824
Species:
Mouse
Synonyms:
pfkfb1, PFKFB1, pfkfb1.S, LOC100475853, Pfkfb1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Pfkfb1
Format:
Viral Particles
Storage:
-80 °C
Human PFKFB1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1)
NCBI Accession:
NM_002625
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5228500
Datasheet
Catalog No. ABIN5228500
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1)
NCBI Accession:
NM_002625
Species:
Human
Synonyms:
pfkfb1, PFKFB1, pfkfb1.S, LOC100475853, Pfkfb1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PFKFB1
Format:
Viral Particles
Storage:
-80 °C
Human PFKFB1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4485619
Datasheet
Catalog No. ABIN4485619
Type:
cDNA
Application:
Protein Expression
Gene:
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1)
Species:
Human
Synonyms:
pfkfb1, PFKFB1, pfkfb1.S, LOC100475853, Pfkfb1
Insert length:
1416 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-XL5
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PFKFB1

  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (pfkfb1)
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (PFKFB1)
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 S homeolog (pfkfb1.S)
  • 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 (LOC100475853)
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (Pfkfb1)
  • F6PK
  • HL2K
  • Pfkfb01
  • PFKFB1
  • PFRX
  • wu:fi11h10
  • zgc:55328

Gene-IDs for different species

Protein level used designations for PFKFB1

  • 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1-like
  • 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1
  • 6PF-2-K/Fru-2,6-P2ASE liver isozyme
  • 6PF-2-K/Fru-2,6-P2ase 1
  • PFK/FBPase 1
  • fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase
  • 6PF-2-K/Fru-2,6-P2ase liver isozyme
  • PFK-2/FBPase-2 gene A
  • 6-phosphofructo-2 kinase /fructose-2,6-biphosphatase 1
Other products related to PFKFB1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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