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PHLPP2 (PH Domain and Leucine Rich Repeat Protein Phosphatase 2, PHLPP2)

Short Description: Protein phosphatase that mediates dephosphorylation of 'Ser-473' of AKT1, 'Ser-660' of PRKCB isoform beta-II and 'Ser- 657' of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradation. Inhibits cancer cell proliferation and may act as a tumor suppressor.
More information related to gene PHLPP2.

Products related to PHLPP2 Gene:

55 results :

Human PHLPP2 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5736979
Datasheet
Catalog No. ABIN5736979
Type:
ORF
Application:
Cloning
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
Species:
Human
Synonyms:
PHLPP2, phlpp2.S, phlpp2, Phlpp2
Insert length:
3972 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse PHLPP2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
NCBI Accession:
NM_001122594
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5112076
Datasheet
Catalog No. ABIN5112076
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
NCBI Accession:
NM_001122594
Species:
Mouse
Synonyms:
PHLPP2, phlpp2.S, phlpp2, Phlpp2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Phlpp2
Format:
Viral Particles
Storage:
-80 °C
Rat PHLPP2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
NCBI Accession:
NM_001109131
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5112078
Datasheet
Catalog No. ABIN5112078
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
NCBI Accession:
NM_001109131
Species:
Rat
Synonyms:
PHLPP2, phlpp2.S, phlpp2, Phlpp2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Phlpp2
Format:
Viral Particles
Storage:
-80 °C
Human PHLPP2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
NCBI Accession:
NM_015020
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5112074
Datasheet
Catalog No. ABIN5112074
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
NCBI Accession:
NM_015020
Species:
Human
Synonyms:
PHLPP2, phlpp2.S, phlpp2, Phlpp2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PHLPP2
Format:
Viral Particles
Storage:
-80 °C
Rat PHLPP2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
NCBI Accession:
NM_001109131
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5227394
Datasheet
Catalog No. ABIN5227394
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
NCBI Accession:
NM_001109131
Species:
Rat
Synonyms:
PHLPP2, phlpp2.S, phlpp2, Phlpp2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Phlpp2
Format:
Viral Particles
Storage:
-80 °C
Mouse PHLPP2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
NCBI Accession:
NM_001122594
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5227392
Datasheet
Catalog No. ABIN5227392
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
NCBI Accession:
NM_001122594
Species:
Mouse
Synonyms:
PHLPP2, phlpp2.S, phlpp2, Phlpp2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Phlpp2
Format:
Viral Particles
Storage:
-80 °C
Human PHLPP2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
NCBI Accession:
NM_015020
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5227390
Datasheet
Catalog No. ABIN5227390
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
NCBI Accession:
NM_015020
Species:
Human
Synonyms:
PHLPP2, phlpp2.S, phlpp2, Phlpp2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PHLPP2
Format:
Viral Particles
Storage:
-80 °C
Human PHLPP2 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4485632
Datasheet
Catalog No. ABIN4485632
Type:
cDNA
Application:
Protein Expression
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
Species:
Human
Synonyms:
PHLPP2, phlpp2.S, phlpp2, Phlpp2
Insert length:
3972 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human PHLPP2 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4629103
Datasheet
Catalog No. ABIN4629103
Type:
cDNA
Application:
Cloning
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
Species:
Human
Synonyms:
PHLPP2, phlpp2.S, phlpp2, Phlpp2
Insert length:
3972 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human PHLPP2 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4420546
Datasheet
Catalog No. ABIN4420546
Type:
cDNA
Application:
Protein Expression
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
Species:
Human
Synonyms:
PHLPP2, phlpp2.S, phlpp2, Phlpp2
Insert length:
3972 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • DYKDDDDK Tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pPB-His-GST
    • pPB-His-MBP
    • pRFP-C-RS
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC-GFP
    • pDONR223
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PHLPP2

  • PH domain and leucine rich repeat protein phosphatase 2 (PHLPP2)
  • PH domain and leucine rich repeat protein phosphatase 2 S homeolog (phlpp2.S)
  • PH domain and leucine rich repeat protein phosphatase 2 (phlpp2)
  • PH domain and leucine rich repeat protein phosphatase 2 (Phlpp2)
  • AI481772
  • C130044A18Rik
  • PHLPPL
  • phlppl
  • Phlppl
  • RGD1562857

Gene-IDs for different species

Protein level used designations for PHLPP2

  • PH domain leucine-rich repeat-containing protein phosphatase 2
  • PH domain and leucine rich repeat protein phosphatase 2
  • PH domain leucine-rich repeat-containing protein phosphatase 2-like
  • GTPase activating protein and VPS9 domains 1
Other products related to PHLPP2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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