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Phospholipase C gamma 1 (phospholipase C, gamma 1, PLCG1)

Short Description: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
More information related to gene Phospholipase C gamma 1.

Products related to Phospholipase C gamma 1 Gene:

56 results :

Rat PLCG1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phospholipase C, gamma 1 (PLCG1)
NCBI Accession:
NM_013187
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5081702
Datasheet
Catalog No. ABIN5081702
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phospholipase C, gamma 1 (PLCG1)
NCBI Accession:
NM_013187
Species:
Rat
Synonyms:
PLCG1, plcg1.L, LOC100633163, Plcg1, plcg1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Plcg1
Format:
Viral Particles
Storage:
-80 °C
Mouse PLCG1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phospholipase C, gamma 1 (PLCG1)
NCBI Accession:
NM_021280
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5081700
Datasheet
Catalog No. ABIN5081700
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phospholipase C, gamma 1 (PLCG1)
NCBI Accession:
NM_021280
Species:
Mouse
Synonyms:
PLCG1, plcg1.L, LOC100633163, Plcg1, plcg1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Plcg1
Format:
Viral Particles
Storage:
-80 °C
Human PLCG1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phospholipase C, gamma 1 (PLCG1)
NCBI Accession:
NM_182811
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5081698
Datasheet
Catalog No. ABIN5081698
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phospholipase C, gamma 1 (PLCG1)
NCBI Accession:
NM_182811
Species:
Human
Synonyms:
PLCG1, plcg1.L, LOC100633163, Plcg1, plcg1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PLCG1
Format:
Viral Particles
Storage:
-80 °C
Rat PLCG1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phospholipase C, gamma 1 (PLCG1)
NCBI Accession:
NM_013187
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5196818
Datasheet
Catalog No. ABIN5196818
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phospholipase C, gamma 1 (PLCG1)
NCBI Accession:
NM_013187
Species:
Rat
Synonyms:
PLCG1, plcg1.L, LOC100633163, Plcg1, plcg1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Plcg1
Format:
Viral Particles
Storage:
-80 °C
Human PLCG1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phospholipase C, gamma 1 (PLCG1)
NCBI Accession:
NM_182811
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5196814
Datasheet
Catalog No. ABIN5196814
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phospholipase C, gamma 1 (PLCG1)
NCBI Accession:
NM_182811
Species:
Human
Synonyms:
PLCG1, plcg1.L, LOC100633163, Plcg1, plcg1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PLCG1
Format:
Viral Particles
Storage:
-80 °C
Mouse PLCG1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phospholipase C, gamma 1 (PLCG1)
NCBI Accession:
NM_021280
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5196816
Datasheet
Catalog No. ABIN5196816
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phospholipase C, gamma 1 (PLCG1)
NCBI Accession:
NM_021280
Species:
Mouse
Synonyms:
PLCG1, plcg1.L, LOC100633163, Plcg1, plcg1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Plcg1
Format:
Viral Particles
Storage:
-80 °C
Rat PLCG1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phospholipase C, gamma 1 (PLCG1)
NCBI Accession:
NM_013187
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5081701
Datasheet
Catalog No. ABIN5081701
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phospholipase C, gamma 1 (PLCG1)
NCBI Accession:
NM_013187
Species:
Rat
Synonyms:
PLCG1, plcg1.L, LOC100633163, Plcg1, plcg1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Plcg1
Format:
Viral Particles
Storage:
-80 °C
Mouse PLCG1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phospholipase C, gamma 1 (PLCG1)
NCBI Accession:
NM_021280
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5081699
Datasheet
Catalog No. ABIN5081699
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phospholipase C, gamma 1 (PLCG1)
NCBI Accession:
NM_021280
Species:
Mouse
Synonyms:
PLCG1, plcg1.L, LOC100633163, Plcg1, plcg1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Plcg1
Format:
Viral Particles
Storage:
-80 °C
Human PLCG1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phospholipase C, gamma 1 (PLCG1)
NCBI Accession:
NM_182811
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5081697
Datasheet
Catalog No. ABIN5081697
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phospholipase C, gamma 1 (PLCG1)
NCBI Accession:
NM_182811
Species:
Human
Synonyms:
PLCG1, plcg1.L, LOC100633163, Plcg1, plcg1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of PLCG1
Format:
Viral Particles
Storage:
-80 °C
Human PLCG1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
phospholipase C, gamma 1 (PLCG1)
NCBI Accession:
NM_182811
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4489765
Datasheet
Catalog No. ABIN4489765
Type:
cDNA
Application:
Protein Expression
Gene:
phospholipase C, gamma 1 (PLCG1)
NCBI Accession:
NM_182811
Species:
Human
Synonyms:
PLCG1, plcg1.L, LOC100633163, Plcg1, plcg1
Insert length:
3876 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-AC-GFP
    • pCMV6-XL4
    • pCas-Guide
    • pRFP-C-RS
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to Phospholipase C gamma 1

  • phospholipase C gamma 1 (PLCG1)
  • phospholipase C gamma 1 L homeolog (plcg1.L)
  • 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (LOC100633163)
  • phospholipase C, gamma 1 (Plcg1)
  • phospholipase C gamma 1 (Plcg1)
  • phospholipase C, gamma 1 (plcg1)
  • AI894140
  • Cded
  • fj46f04
  • NCKAP3
  • nckap3
  • Plc-1
  • Plc-gamma1
  • PLC-II
  • plc-ii
  • PLC1
  • plc1
  • PLC148
  • plc148
  • Plcg-1
  • PLCgamma1
  • plcgamma1
  • PPLCA
  • wu:fj46f04
  • wu:fj57a05

Gene-IDs for different species

Protein level used designations for Phospholipase C gamma 1

  • 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate
  • 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
  • 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1
  • 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1
  • PLC-148
  • PLC-gamma-1
  • inositoltrisphosphohydrolase
  • monophosphatidylinositol phosphodiesterase
  • phosphatidylinositol phospholipase C
  • phosphoinositidase C
  • phosphoinositide phospholipase C
  • phosphoinositide phospholipase C-gamma-1
  • phospholipase C, gamma 1 (formerly subtype 148)
  • phospholipase C-148
  • phospholipase C-II
  • phospholipase C-gamma-1
  • triphosphoinositide phosphodiesterase
  • PLC gamma 1
  • phospholipase C-gamma-1b
  • phospholipase C, gamma 1
  • PLC-II
  • cell differentiation and embryonic development
  • dead beat
  • ded
Other products related to Phospholipase C gamma 1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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