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PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant), PKD1)

Short Description: This gene encodes a member of the polycystin protein family. The encoded glycoprotein contains a large N-terminal extracellular region, multiple transmembrane domains and a cytoplasmic C-tail. It is an integral membrane protein that functions as a regulator of calcium permeable cation channels and intracellular calcium homoeostasis. It is also involved in cell-cell/matrix interactions and may modulate G-protein-coupled signal-transduction pathways. It plays a role in renal tubular development, and mutations in this gene cause autosomal dominant polycystic kidney disease type 1 (ADPKD1). ADPKD1 is characterized by the growth of fluid-filled cysts that replace normal renal tissue and result in end-stage renal failure. Splice variants encoding different isoforms have been noted for this gene. Also, six pseudogenes, closely linked in a known duplicated region on chromosome 16p, have been described. [provided by RefSeq, Oct 2008].
More information related to gene PKD1.

Products related to PKD1 Gene:

40 results :

Human PKD1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)
NCBI Accession:
NM_000296
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5255721
Datasheet
Catalog No. ABIN5255721
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)
NCBI Accession:
NM_000296
Species:
Human
Synonyms:
PKD1, Pkd1, LOC749291
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PKD1
Format:
Viral Particles
Storage:
-80 °C
Mouse PKD1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)
NCBI Accession:
NM_013630
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5255723
Datasheet
Catalog No. ABIN5255723
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)
NCBI Accession:
NM_013630
Species:
Mouse
Synonyms:
PKD1, Pkd1, LOC749291
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Pkd1
Format:
Viral Particles
Storage:
-80 °C
Mouse PKD1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)
NCBI Accession:
NM_013630
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5140226
Datasheet
Catalog No. ABIN5140226
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)
NCBI Accession:
NM_013630
Species:
Mouse
Synonyms:
PKD1, Pkd1, LOC749291
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Pkd1
Format:
Viral Particles
Storage:
-80 °C
Human PKD1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)
NCBI Accession:
NM_000296
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5140224
Datasheet
Catalog No. ABIN5140224
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)
NCBI Accession:
NM_000296
Species:
Human
Synonyms:
PKD1, Pkd1, LOC749291
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PKD1
Format:
Viral Particles
Storage:
-80 °C
Mouse PKD1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)
NCBI Accession:
NM_013630
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5255722
Datasheet
Catalog No. ABIN5255722
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)
NCBI Accession:
NM_013630
Species:
Mouse
Synonyms:
PKD1, Pkd1, LOC749291
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Pkd1
Format:
Viral Particles
Storage:
-80 °C
Human PKD1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)
NCBI Accession:
NM_000296
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5255720
Datasheet
Catalog No. ABIN5255720
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)
NCBI Accession:
NM_000296
Species:
Human
Synonyms:
PKD1, Pkd1, LOC749291
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of PKD1
Format:
Viral Particles
Storage:
-80 °C
Mouse PKD1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)
NCBI Accession:
NM_013630
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5140225
Datasheet
Catalog No. ABIN5140225
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)
NCBI Accession:
NM_013630
Species:
Mouse
Synonyms:
PKD1, Pkd1, LOC749291
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Pkd1
Format:
Viral Particles
Storage:
-80 °C
Human PKD1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)
NCBI Accession:
NM_000296
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5140223
Datasheet
Catalog No. ABIN5140223
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)
NCBI Accession:
NM_000296
Species:
Human
Synonyms:
PKD1, Pkd1, LOC749291
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of PKD1
Format:
Viral Particles
Storage:
-80 °C
Rat PKD1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)
NCBI Accession:
NM_001257352
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5751628
Datasheet
Catalog No. ABIN5751628
Type:
ORF
Application:
Cloning
Gene:
Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)
NCBI Accession:
NM_001257352
Species:
Rat
Synonyms:
PKD1, Pkd1, LOC749291
Insert length:
12879 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse PKD1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)
NCBI Accession:
NM_013630
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5751627
Datasheet
Catalog No. ABIN5751627
Type:
ORF
Application:
Cloning
Gene:
Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)
NCBI Accession:
NM_013630
Species:
Mouse
Synonyms:
PKD1, Pkd1, LOC749291
Insert length:
12882 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • His tag
    • GFP tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pLenti-C-Myc-DDK
    • pORF
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pRFP-C-RS
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • shRNA
    • ORF
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Liquid
    • Lyophilized
    • Viral Particles

Synonyms and alternative names related to PKD1

  • polycystin 1, transient receptor potential channel interacting (PKD1)
  • polycystin 1, transient receptor poteintial channel interacting (Pkd1)
  • polycystin 1, transient receptor potential channel interacting (Pkd1)
  • polycystin-1 (LOC749291)
  • mFLJ00285
  • PBP
  • Pc-1
  • PC1
  • TRPP1

Gene-IDs for different species

Protein level used designations for PKD1

  • autosomal dominant polycystic kidney disease 1 protein
  • polycystic kidney disease-associated protein
  • polycystin 1
  • polycystin-1
  • transient receptor potential cation channel, subfamily P, member 1
  • autosomal dominant polycystic kidney disease 1 protein homolog
  • polycystic kidney disease 1 homolog; polycystin-1
  • polycystic kidney disease 1 (autosomal dominant)
  • polycystic kidney disease protein 1
Other products related to PKD1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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