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PKM (Pyruvate Kinase M1/2, PKM)

Short Description: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011].
More information related to gene PKM.

Products related to PKM Gene:

16 results :

Human PKM ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Pyruvate Kinase M1/2 (PKM)
NCBI Accession:
NM_001206797
Gene ID:
5315 (Human, PKM)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4925442
Datasheet
Catalog No. ABIN4925442
Type:
ORF
Application:
Protein Expression
Gene:
Pyruvate Kinase M1/2 (PKM)
NCBI Accession:
NM_001206797
Gene ID:
5315 (Human, PKM)
Synonyms:
PKM, Pkm, PyK, pkma, pkm, LOC710798, pyk, pk, LOC100534543, pkm.S, pkmb
Insert length:
1374 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Sequencing Primer:
    • Forward primer: 5'-TAATACGACTCACTATAGGG-3'
    • Reverse primer: 5'-CCTCGACTGTGCCTTCTA-3'
Components:
The GenEZ ORF clone is delivered as 10 μg of lyophilized plasmid DNA in a vial.
Format:
Lyophilized
Storage:
RT/-20 °C
Human PKM ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Pyruvate Kinase M1/2 (PKM)
NCBI Accession:
NM_002654
Gene ID:
5315 (Human, PKM)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4936580
Datasheet
Catalog No. ABIN4936580
Type:
ORF
Application:
Protein Expression
Gene:
Pyruvate Kinase M1/2 (PKM)
NCBI Accession:
NM_002654
Gene ID:
5315 (Human, PKM)
Synonyms:
PKM, Pkm, PyK, pkma, pkm, LOC710798, pyk, pk, LOC100534543, pkm.S, pkmb
Insert length:
1596 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Sequencing Primer:
    • Forward primer: 5'-TAATACGACTCACTATAGGG-3'
    • Reverse primer: 5'-CCTCGACTGTGCCTTCTA-3'
Components:
The GenEZ ORF clone is delivered as 10 μg of lyophilized plasmid DNA in a vial.
Format:
Lyophilized
Storage:
RT/-20 °C
Human PKM ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Pyruvate Kinase M1/2 (PKM)
NCBI Accession:
NM_182470
Gene ID:
5315 (Human, PKM)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4918584
Datasheet
Catalog No. ABIN4918584
Type:
ORF
Application:
Protein Expression
Gene:
Pyruvate Kinase M1/2 (PKM)
NCBI Accession:
NM_182470
Gene ID:
5315 (Human, PKM)
Synonyms:
PKM, Pkm, PyK, pkma, pkm, LOC710798, pyk, pk, LOC100534543, pkm.S, pkmb
Insert length:
1596 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Sequencing Primer:
    • Forward primer: 5'-TAATACGACTCACTATAGGG-3'
    • Reverse primer: 5'-CCTCGACTGTGCCTTCTA-3'
Components:
The GenEZ ORF clone is delivered as 10 μg of lyophilized plasmid DNA in a vial.
Format:
Lyophilized
Storage:
RT/-20 °C
Human PKM siRNA Oligo
RNAi PKM Species: Human HPLC purified
Application:
RNA Interference
Gene:
Pyruvate Kinase M1/2
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3343318
Datasheet
Catalog No. ABIN3343318
Application:
RNA Interference
Gene:
Pyruvate Kinase M1/2
Species:
Human
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • PKM (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Human PKM ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Pyruvate Kinase M1/2 (PKM)
NCBI Accession:
NM_001206798
Gene ID:
5315 (Human, PKM)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4925443
Datasheet
Catalog No. ABIN4925443
Type:
ORF
Application:
Protein Expression
Gene:
Pyruvate Kinase M1/2 (PKM)
NCBI Accession:
NM_001206798
Gene ID:
5315 (Human, PKM)
Synonyms:
PKM, Pkm, PyK, pkma, pkm, LOC710798, pyk, pk, LOC100534543, pkm.S, pkmb
Insert length:
1551 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Sequencing Primer:
    • Forward primer: 5'-TAATACGACTCACTATAGGG-3'
    • Reverse primer: 5'-CCTCGACTGTGCCTTCTA-3'
Components:
The GenEZ ORF clone is delivered as 10 μg of lyophilized plasmid DNA in a vial.
Format:
Lyophilized
Storage:
RT/-20 °C
Human PKM ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Pyruvate Kinase M1/2 (PKM)
NCBI Accession:
NM_001206799
Gene ID:
5315 (Human, PKM)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4925444
Datasheet
Catalog No. ABIN4925444
Type:
ORF
Application:
Protein Expression
Gene:
Pyruvate Kinase M1/2 (PKM)
NCBI Accession:
NM_001206799
Gene ID:
5315 (Human, PKM)
Synonyms:
PKM, Pkm, PyK, pkma, pkm, LOC710798, pyk, pk, LOC100534543, pkm.S, pkmb
Insert length:
1611 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Sequencing Primer:
    • Forward primer: 5'-TAATACGACTCACTATAGGG-3'
    • Reverse primer: 5'-CCTCGACTGTGCCTTCTA-3'
Components:
The GenEZ ORF clone is delivered as 10 μg of lyophilized plasmid DNA in a vial.
Format:
Lyophilized
Storage:
RT/-20 °C
Human PKM ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Pyruvate Kinase M1/2 (PKM)
NCBI Accession:
NM_001206796
Gene ID:
5315 (Human, PKM)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4925441
Datasheet
Catalog No. ABIN4925441
Type:
ORF
Application:
Protein Expression
Gene:
Pyruvate Kinase M1/2 (PKM)
NCBI Accession:
NM_001206796
Gene ID:
5315 (Human, PKM)
Synonyms:
PKM, Pkm, PyK, pkma, pkm, LOC710798, pyk, pk, LOC100534543, pkm.S, pkmb
Insert length:
1818 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Sequencing Primer:
    • Forward primer: 5'-TAATACGACTCACTATAGGG-3'
    • Reverse primer: 5'-CCTCGACTGTGCCTTCTA-3'
Components:
The GenEZ ORF clone is delivered as 10 μg of lyophilized plasmid DNA in a vial.
Format:
Lyophilized
Storage:
RT/-20 °C
Human PKM cDNA Clone in Mammalian Expression Vector
cDNA PExp Mammalian Expression Vector pCMV6-XL5 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Kinase M1/2 (PKM)
NCBI Accession:
NM_182470,NP_872270
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL5
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3391515
Datasheet
Catalog No. ABIN3391515
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Kinase M1/2 (PKM)
NCBI Accession:
NM_182470,NP_872270
Species:
Human
Synonyms:
PKM, Pkm, PyK, pkma, pkm, LOC710798, pyk, pk, LOC100534543, pkm.S, pkmb
Insert length:
2300 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL5
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Empty vector controls:
ABIN4948184
Sequencing Primer:
  • VP1.5 (forward) 5'GGACTTTCCAAAATGTCG 3'
  • XL39 (reverse) 5'ATTAGGACAAGGCTGGTGGG 3'
Components:
  • The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA.
  • The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.
Format:
Lyophilized
Storage:
RT,-20 °C
Rat PKM cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Kinase M1/2 (PKM)
NCBI Accession:
NM_053297,NP_445749
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3364638
Datasheet
Catalog No. ABIN3364638
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Kinase M1/2 (PKM)
NCBI Accession:
NM_053297,NP_445749
Species:
Rat
Synonyms:
PKM, Pkm, PyK, pkma, pkm, LOC710798, pyk, pk, LOC100534543, pkm.S, pkmb
Insert length:
1596 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Empty vector controls:
ABIN4948181
Sequencing Primer:
  • VP1.5 (forward) 5'GGACTTTCCAAAATGTCG 3'
  • XL39 (reverse) 5'ATTAGGACAAGGCTGGTGGG 3'
Components:
  • The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA.
  • The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.
Format:
Lyophilized
Storage:
RT,-20 °C
Mouse PKM cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Kinase M1/2 (PKM)
NCBI Accession:
NM_001253883,NP_001240812
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3364637
Datasheet
Catalog No. ABIN3364637
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Kinase M1/2 (PKM)
NCBI Accession:
NM_001253883,NP_001240812
Species:
Mouse
Synonyms:
PKM, Pkm, PyK, pkma, pkm, LOC710798, pyk, pk, LOC100534543, pkm.S, pkmb
Insert length:
1596 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Empty vector controls:
ABIN4948181
Sequencing Primer:
  • VP1.5 (forward) 5'GGACTTTCCAAAATGTCG 3'
  • XL39 (reverse) 5'ATTAGGACAAGGCTGGTGGG 3'
Components:
  • The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA.
  • The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.
Format:
Lyophilized
Storage:
RT,-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • DYKDDDDK Tag
    • Un-conjugated
    • Myc-DYKDDDDK Tag
    • GFP tag
  • Vector Backbone
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-Entry
    • pCMV6-XL5
    • pCas-Guide
    • pCMV6-XL4
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
  • Insert
    • ORF
    • cDNA
    • gRNA + Cas9
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Chloramphenicol
    • Kanamycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
  • Promoter
    • CMV Promoter
    • Enhanced CMV Promoter
    • T7 Promoter
    • U6 Promoter
  • Format
    • Lyophilized
    • Viral Particles

Synonyms and alternative names related to PKM

  • pyruvate kinase M1/2 (PKM)
  • pyruvate kinase, muscle (Pkm)
  • Pyruvate kinase (PyK)
  • pyruvate kinase M1/2a (pkma)
  • pyruvate kinase, muscle (pkm)
  • pyruvate kinase, muscle (PKM)
  • pyruvate kinase PKM (LOC710798)
  • pyruvate kinase (PK) (pyk)
  • pyruvate kinase PKM (pk)
  • pyruvate kinase (pk)
  • pyruvate kinase PKM (LOC100534543)
  • pyruvate kinase M1/2 S homeolog (pkm.S)
  • pyruvate kinase M1/2 (Pkm)
  • pyruvate kinase M1/2b (pkmb)
  • AA414905
  • AL024370
  • AL024424
  • cb1029
  • CG7070
  • CTHBP
  • Dmel\\CG7070
  • fj33f03
  • MGC53388
  • OIP3
  • Pk-2
  • Pk-3
  • PK-S
  • PK3
  • Pk3
  • pk3
  • PKM
  • PKM2
  • Pkm2
  • pkm2
  • pkm2a
  • pkm2b
  • PKM12
  • PYK
  • Pyk
  • TCB
  • THBP1
  • wu:fj33f03
  • zgc:92037

Gene-IDs for different species

Protein level used designations for PKM

  • OIP-3
  • OPA-interacting protein 3
  • PK, muscle type
  • cytosolic thyroid hormone-binding protein
  • p58
  • pyruvate kinase 2/3
  • pyruvate kinase PKM
  • pyruvate kinase isozymes M1/M2
  • pyruvate kinase muscle isozyme
  • thyroid hormone-binding protein 1
  • thyroid hormone-binding protein, cytosolic
  • tumor M2-PK
  • pyruvate kinase 3
  • CG7070-PA
  • CG7070-PB
  • PyK-PA
  • PyK-PB
  • pyruvate kinase
  • pyruvate kinase, muscle
  • pyruvate kinase M
  • ATP:pyruvate 2-o-phosphotransferase
  • Pyruvate kinase isozymes M1/M2
  • Pyruvate kinase muscle isozyme
  • CTHBP
  • cytosolic thyroid hormone binding protein/pyruvate kinase type M2
  • Pyruvate kinase PKM
  • pyruvate kinase, muscle, b
Other products related to PKM such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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