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PRKG1 (Protein Kinase, CGMP-Dependent, Type I, PRKG1)

Short Description: Mammals have three different isoforms of cyclic GMP-dependent protein kinase (Ialpha, Ibeta, and II). These PRKG isoforms act as key mediators of the nitric oxide/cGMP signaling pathway and are important components of many signal transduction processes in diverse cell types. This PRKG1 gene on human chromosome 10 encodes the soluble Ialpha and Ibeta isoforms of PRKG by alternative transcript splicing. A separate gene on human chromosome 4, PRKG2, encodes the membrane-bound PRKG isoform II. The PRKG1 proteins play a central role in regulating cardiovascular and neuronal functions in addition to relaxing smooth muscle tone, preventing platelet aggregation, and modulating cell growth. This gene is most strongly expressed in all types of smooth muscle, platelets, cerebellar Purkinje cells, hippocampal neurons, and the lateral amygdala. Isoforms Ialpha and Ibeta have identical cGMP-binding and catalytic domains but differ in their leucine/isoleucine zipper and autoinhibitory sequences and therefore differ in their dimerization substrates and kinase enzyme activity. [provided by RefSeq, Sep 2011].
More information related to gene PRKG1.

Products related to PRKG1 Gene:

66 results :

Human PRKG1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4485729
Datasheet
Catalog No. ABIN4485729
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
Species:
Human
Synonyms:
prkg1a, PRKG1, prkg1, Prkg1
Insert length:
2061 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat PRKG1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_001105731
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5231318
Datasheet
Catalog No. ABIN5231318
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_001105731
Species:
Rat
Synonyms:
prkg1a, PRKG1, prkg1, Prkg1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Prkg1
Format:
Viral Particles
Storage:
-80 °C
Mouse PRKG1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_001013833
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5231316
Datasheet
Catalog No. ABIN5231316
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_001013833
Species:
Mouse
Synonyms:
prkg1a, PRKG1, prkg1, Prkg1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Prkg1
Format:
Viral Particles
Storage:
-80 °C
Human PRKG1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_006258
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5231314
Datasheet
Catalog No. ABIN5231314
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_006258
Species:
Human
Synonyms:
prkg1a, PRKG1, prkg1, Prkg1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PRKG1
Format:
Viral Particles
Storage:
-80 °C
Rat PRKG1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_001105731
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5115966
Datasheet
Catalog No. ABIN5115966
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_001105731
Species:
Rat
Synonyms:
prkg1a, PRKG1, prkg1, Prkg1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Prkg1
Format:
Viral Particles
Storage:
-80 °C
Mouse PRKG1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_001013833
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5115964
Datasheet
Catalog No. ABIN5115964
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_001013833
Species:
Mouse
Synonyms:
prkg1a, PRKG1, prkg1, Prkg1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Prkg1
Format:
Viral Particles
Storage:
-80 °C
Human PRKG1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_006258
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5115962
Datasheet
Catalog No. ABIN5115962
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_006258
Species:
Human
Synonyms:
prkg1a, PRKG1, prkg1, Prkg1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PRKG1
Format:
Viral Particles
Storage:
-80 °C
Human PRKG1 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4838167
Datasheet
Catalog No. ABIN4838167
Type:
cDNA
Application:
Cloning
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
Species:
Human
Synonyms:
prkg1a, PRKG1, prkg1, Prkg1
Insert length:
2061 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human PRKG1 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4629200
Datasheet
Catalog No. ABIN4629200
Type:
cDNA
Application:
Cloning
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
Species:
Human
Synonyms:
prkg1a, PRKG1, prkg1, Prkg1
Insert length:
2061 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human PRKG1 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4420643
Datasheet
Catalog No. ABIN4420643
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
Species:
Human
Synonyms:
prkg1a, PRKG1, prkg1, Prkg1
Insert length:
2061 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-Neo
    • pCMV6-XL4
    • pDONR223
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PRKG1

  • protein kinase, cGMP-dependent, type Ia (prkg1a)
  • protein kinase, cGMP-dependent, type I (PRKG1)
  • protein kinase, cGMP-dependent, type I (prkg1)
  • protein kinase, cGMP-dependent, type 1 (Prkg1)
  • protein kinase, cGMP-dependent, type I (Prkg1)
  • 1
  • AW125416
  • cGK
  • cGk1
  • cGK 1
  • cGK1
  • cGKI
  • CGKI
  • cGKI-alpha
  • cGKI-BETA
  • cGKI-beta
  • Gm19690
  • PKG
  • Pkgi
  • prkg1
  • PRKG1B
  • Prkg1b
  • Prkg1beta
  • PRKGR1B
  • Prkgr1b
  • zgc:63955

Gene-IDs for different species

Protein level used designations for PRKG1

  • cGMP-dependent protein kinase 1
  • protein kinase, cGMP-dependent, type I
  • cGMP-dependent protein kinase 1, beta isozyme
  • cGMP-dependent protein kinase I alpha
  • cGK I alpha
  • cGMP-dependent protein kinase 1-like
  • cGMP dependent protein kinase type 1
  • protein kinase, cGMP-dependent, regulatory, type I, beta
  • CGK 1 alpha
  • cGK 1 beta
  • cGK1
  • cGKI-alpha
  • cGMP-dependent protein kinase 1, alpha isozyme
  • cGMP-dependent protein kinase I
  • cGK 1
  • PKG1 alpha
  • cGMP-dependent protein kinase type 1 alpha
  • cGMP-dependent protein kinase type I beta
Other products related to PRKG1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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