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RAD50 (RAD50 Homolog (S. Cerevisiae), RAD50)

Short Description: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010].
More information related to gene RAD50.

Products related to RAD50 Gene:

55 results :

Human RAD50 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
RAD50 Homolog (S. Cerevisiae) (RAD50)
NCBI Accession:
NM_005732
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5757294
Datasheet
Catalog No. ABIN5757294
Type:
ORF
Application:
Cloning
Gene:
RAD50 Homolog (S. Cerevisiae) (RAD50)
NCBI Accession:
NM_005732
Species:
Human
Synonyms:
RAD50, Rad50, rad50, rad50.L, LOC658288, LOC726642, rad-50
Insert length:
3939 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat RAD50 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
RAD50 Homolog (S. Cerevisiae) (RAD50)
NCBI Accession:
NM_022246
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5266971
Datasheet
Catalog No. ABIN5266971
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
RAD50 Homolog (S. Cerevisiae) (RAD50)
NCBI Accession:
NM_022246
Species:
Rat
Synonyms:
RAD50, Rad50, rad50, rad50.L, LOC658288, LOC726642, rad-50
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Rad50
Format:
Viral Particles
Storage:
-80 °C
Human RAD50 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
RAD50 Homolog (S. Cerevisiae) (RAD50)
NCBI Accession:
NM_005732
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5266967
Datasheet
Catalog No. ABIN5266967
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
RAD50 Homolog (S. Cerevisiae) (RAD50)
NCBI Accession:
NM_005732
Species:
Human
Synonyms:
RAD50, Rad50, rad50, rad50.L, LOC658288, LOC726642, rad-50
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of RAD50
Format:
Viral Particles
Storage:
-80 °C
Mouse RAD50 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
RAD50 Homolog (S. Cerevisiae) (RAD50)
NCBI Accession:
NM_009012
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5266969
Datasheet
Catalog No. ABIN5266969
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
RAD50 Homolog (S. Cerevisiae) (RAD50)
NCBI Accession:
NM_009012
Species:
Mouse
Synonyms:
RAD50, Rad50, rad50, rad50.L, LOC658288, LOC726642, rad-50
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Rad50
Format:
Viral Particles
Storage:
-80 °C
Human RAD50 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
RAD50 Homolog (S. Cerevisiae) (RAD50)
NCBI Accession:
NM_005732
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4490002
Datasheet
Catalog No. ABIN4490002
Type:
cDNA
Application:
Protein Expression
Gene:
RAD50 Homolog (S. Cerevisiae) (RAD50)
NCBI Accession:
NM_005732
Species:
Human
Synonyms:
RAD50, Rad50, rad50, rad50.L, LOC658288, LOC726642, rad-50
Insert length:
3939 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat RAD50 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
RAD50 Homolog (S. Cerevisiae) (RAD50)
NCBI Accession:
NM_022246
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5151411
Datasheet
Catalog No. ABIN5151411
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
RAD50 Homolog (S. Cerevisiae) (RAD50)
NCBI Accession:
NM_022246
Species:
Rat
Synonyms:
RAD50, Rad50, rad50, rad50.L, LOC658288, LOC726642, rad-50
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Rad50
Format:
Viral Particles
Storage:
-80 °C
Mouse RAD50 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
RAD50 Homolog (S. Cerevisiae) (RAD50)
NCBI Accession:
NM_009012
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5151409
Datasheet
Catalog No. ABIN5151409
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
RAD50 Homolog (S. Cerevisiae) (RAD50)
NCBI Accession:
NM_009012
Species:
Mouse
Synonyms:
RAD50, Rad50, rad50, rad50.L, LOC658288, LOC726642, rad-50
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Rad50
Format:
Viral Particles
Storage:
-80 °C
Human RAD50 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
RAD50 Homolog (S. Cerevisiae) (RAD50)
NCBI Accession:
NM_005732
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5151407
Datasheet
Catalog No. ABIN5151407
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
RAD50 Homolog (S. Cerevisiae) (RAD50)
NCBI Accession:
NM_005732
Species:
Human
Synonyms:
RAD50, Rad50, rad50, rad50.L, LOC658288, LOC726642, rad-50
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of RAD50
Format:
Viral Particles
Storage:
-80 °C
Mouse RAD50 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
RAD50 Homolog (S. Cerevisiae) (RAD50)
NCBI Accession:
NM_009012
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5757295
Datasheet
Catalog No. ABIN5757295
Type:
ORF
Application:
Cloning
Gene:
RAD50 Homolog (S. Cerevisiae) (RAD50)
NCBI Accession:
NM_009012
Species:
Mouse
Synonyms:
RAD50, Rad50, rad50, rad50.L, LOC658288, LOC726642, rad-50
Insert length:
3939 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat RAD50 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
RAD50 Homolog (S. Cerevisiae) (RAD50)
NCBI Accession:
NM_022246
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5757296
Datasheet
Catalog No. ABIN5757296
Type:
ORF
Application:
Cloning
Gene:
RAD50 Homolog (S. Cerevisiae) (RAD50)
NCBI Accession:
NM_022246
Species:
Rat
Synonyms:
RAD50, Rad50, rad50, rad50.L, LOC658288, LOC726642, rad-50
Insert length:
3939 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pRFP-C-RS
    • pCMV6-AC-GFP
    • pCMV6-XL4
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • shRNA
    • ORF
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to RAD50

  • RAD50 double strand break repair protein (RAD50)
  • RAD50 double strand break repair protein (Rad50)
  • CG6339 gene product from transcript CG6339-RE (rad50)
  • RAD50 homolog, double strand break repair protein L homeolog (rad50.L)
  • rad50 (LOC658288)
  • DNA repair protein RAD50 (LOC726642)
  • RAD50 homolog, double strand break repair protein (rad50)
  • DNA repair-recombination protein (RAD50) (RAD50)
  • MRX complex DNA-binding subunit (RAD50)
  • DNA repair protein Rad50 (rad50)
  • RAD50 recombination protein (RAD50)
  • Rad50 DNA repair/recombination protein (Rad50)
  • DNA repair protein rad-50 (rad-50)
  • 6339
  • ATRAD50
  • CG6339
  • Dmel\\CG6339
  • Dmrad50
  • DNA REPAIR-RECOMBINATION PROTEIN
  • F22D22.28
  • F22D22_28
  • hRad50
  • im:6906849
  • Mrell
  • NBSLD
  • RAD50
  • Rad50
  • Rad50l
  • RAD502
  • si:ch211-79h18.3
  • SPAP4C9.01c

Gene-IDs for different species

Protein level used designations for RAD50

  • DNA repair protein RAD50
  • mRad50
  • CG6339-PD
  • CG6339-PE
  • rad50-PD
  • rad50-PE
  • RAD50 homolog (S. cerevisiae)
  • RAD50 homolog
  • GLEAN_15093
  • Rad50p
  • Subunit of MRX complex, with Mre11p and Xrs2p, involved in processing double-strand DNA breaks in vegetative cells, initiation of meiotic DSBs, telomere maintenance, and nonhomologous end joining
  • Rad50 DNA repair/recombination protein
  • DNA repair protein RAD50-like
Other products related to RAD50 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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