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RECQL2 (Werner syndrome RecQ like helicase, WRN)

Short Description: This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging. [provided by RefSeq, Jul 2008].
More information related to gene RECQL2.

Products related to RECQL2 Gene:

41 results :

Mouse WRN CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Werner syndrome RecQ like helicase (WRN)
NCBI Accession:
NM_011721
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5239125
Datasheet
Catalog No. ABIN5239125
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Werner syndrome RecQ like helicase (WRN)
NCBI Accession:
NM_011721
Species:
Mouse
Synonyms:
WRN, LOC9327212, blm, Wrn, wrn.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Wrn
Format:
Viral Particles
Storage:
-80 °C
Human WRN CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Werner syndrome RecQ like helicase (WRN)
NCBI Accession:
NM_000553
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5239123
Datasheet
Catalog No. ABIN5239123
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Werner syndrome RecQ like helicase (WRN)
NCBI Accession:
NM_000553
Species:
Human
Synonyms:
WRN, LOC9327212, blm, Wrn, wrn.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of WRN
Format:
Viral Particles
Storage:
-80 °C
Human WRN CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Werner syndrome RecQ like helicase (WRN)
NCBI Accession:
NM_000553
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5123726
Datasheet
Catalog No. ABIN5123726
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Werner syndrome RecQ like helicase (WRN)
NCBI Accession:
NM_000553
Species:
Human
Synonyms:
WRN, LOC9327212, blm, Wrn, wrn.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of WRN
Format:
Viral Particles
Storage:
-80 °C
Mouse WRN CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Werner syndrome RecQ like helicase (WRN)
NCBI Accession:
NM_011721
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5123728
Datasheet
Catalog No. ABIN5123728
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Werner syndrome RecQ like helicase (WRN)
NCBI Accession:
NM_011721
Species:
Mouse
Synonyms:
WRN, LOC9327212, blm, Wrn, wrn.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Wrn
Format:
Viral Particles
Storage:
-80 °C
Mouse WRN CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Werner syndrome RecQ like helicase (WRN)
NCBI Accession:
NM_011721
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5239124
Datasheet
Catalog No. ABIN5239124
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Werner syndrome RecQ like helicase (WRN)
NCBI Accession:
NM_011721
Species:
Mouse
Synonyms:
WRN, LOC9327212, blm, Wrn, wrn.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Wrn
Format:
Viral Particles
Storage:
-80 °C
Human WRN CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Werner syndrome RecQ like helicase (WRN)
NCBI Accession:
NM_000553
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5239122
Datasheet
Catalog No. ABIN5239122
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Werner syndrome RecQ like helicase (WRN)
NCBI Accession:
NM_000553
Species:
Human
Synonyms:
WRN, LOC9327212, blm, Wrn, wrn.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of WRN
Format:
Viral Particles
Storage:
-80 °C
Human WRN CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Werner syndrome RecQ like helicase (WRN)
NCBI Accession:
NM_000553
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5123725
Datasheet
Catalog No. ABIN5123725
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Werner syndrome RecQ like helicase (WRN)
NCBI Accession:
NM_000553
Species:
Human
Synonyms:
WRN, LOC9327212, blm, Wrn, wrn.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of WRN
Format:
Viral Particles
Storage:
-80 °C
Mouse WRN CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Werner syndrome RecQ like helicase (WRN)
NCBI Accession:
NM_011721
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5123727
Datasheet
Catalog No. ABIN5123727
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Werner syndrome RecQ like helicase (WRN)
NCBI Accession:
NM_011721
Species:
Mouse
Synonyms:
WRN, LOC9327212, blm, Wrn, wrn.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Wrn
Format:
Viral Particles
Storage:
-80 °C
Mouse WRN ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Werner syndrome RecQ like helicase (WRN)
NCBI Accession:
NM_011721
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5743111
Datasheet
Catalog No. ABIN5743111
Type:
ORF
Application:
Cloning
Gene:
Werner syndrome RecQ like helicase (WRN)
NCBI Accession:
NM_011721
Species:
Mouse
Synonyms:
WRN, LOC9327212, blm, Wrn, wrn.L
Insert length:
4206 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse WRN ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Werner syndrome RecQ like helicase (WRN)
NCBI Accession:
NM_001122822
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5743112
Datasheet
Catalog No. ABIN5743112
Type:
ORF
Application:
Cloning
Gene:
Werner syndrome RecQ like helicase (WRN)
NCBI Accession:
NM_001122822
Species:
Mouse
Synonyms:
WRN, LOC9327212, blm, Wrn, wrn.L
Insert length:
4206 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
  • Reactivity
    • Mouse
    • Human
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRFP-C-RS
    • pRS
    • pCMV6-AC-GFP
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to RECQL2

  • Werner syndrome RecQ like helicase (WRN)
  • mediator of RNA polymerase II transcription subunit 34 (LOC9327212)
  • Bloom syndrome RecQ like helicase (blm)
  • Werner syndrome RecQ like helicase (Wrn)
  • Werner syndrome, RecQ helicase-like L homeolog (wrn.L)
  • AI846146
  • ffa-1
  • recq2
  • RECQ3
  • RECQL2
  • recql2
  • RECQL3
  • recql3
  • RGD1564788
  • xBLM
  • xwrn

Gene-IDs for different species

Protein level used designations for RECQL2

  • DNA helicase, RecQ-like type 3
  • Werner syndrome ATP-dependent helicase
  • exonuclease WRN
  • recQ protein-like 2
  • RECQL2
  • Werner syndrome ATP-dependent helicase homolog
  • focus forming activity 1
  • focus-forming activity 1
  • Werner syndrome, RecQ helicase-like
  • similar to Werner syndrome helicase homolog
Other products related to RECQL2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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