RP1 (Retinitis Pigmentosa 1 (Autosomal Dominant), RP1)
Short Description: This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains, which bind microtubules and regulate microtubule polymerization. The encoded protein is a photoreceptor microtubule-associated protein and is required for correct stacking of outer segment disc. This protein and the RP1L1 protein, another retinal-specific protein, play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. Because of its response to in vivo retinal oxygen levels, this protein was initially named ORP1 (oxygen-regulated protein-1). This protein was subsequently designated RP1 (retinitis pigmentosa 1) when it was found that mutations in this gene cause autosomal dominant retinitis pigmentosa. Mutations in this gene also cause autosomal recessive retinitis pigmentosa. Two transcript variants encoding distinct isoforms are resulted from alternative promoters and alternative splicing. [provided by RefSeq, Sep 2010].
More information related to gene RP1.
More information related to gene RP1.
Products related to RP1 Gene:
Recommended next Filters:
6 results :
RNAi
RP1
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- Retinitis Pigmentosa 1 (Autosomal Dominant)
- Species:
- Mouse
- Purification:
- HPLC purified
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Retinitis Pigmentosa 1 (Autosomal Dominant) (RP1)
- Species:
- Mouse
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Retinitis Pigmentosa 1 (Autosomal Dominant) (RP1)
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Retinitis Pigmentosa 1 (Autosomal Dominant) (RP1)
- NCBI Accession:
- NM_006269,NP_006260
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Retinitis Pigmentosa 1 (Autosomal Dominant) (RP1)
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Retinitis Pigmentosa 1 (Autosomal Dominant) (RP1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Synonyms and alternative names related to RP1
- RP1, axonemal microtubule associated L homeolog (rp1.L)
- RP1, axonemal microtubule associated (RP1)
- retinitis pigmentosa 1 (autosomal dominant) (rp1)
- uncharacterized LOC100355685 (LOC100355685)
- RP1, axonemal microtubule associated (Rp1)
- retinitis pigmentosa 1 (human) (Rp1)
- Dcdc3
- DCDC4A
- mG145
- MGC83581
- orp1
- ORP1
- Orp1
- Rp1h
Gene-IDs for different species
Protein level used designations for RP1
- retinitis pigmentosa 1 (autosomal dominant)
- retinitis pigmentosa RP1 protein
- oxygen-regulated protein 1-like
- oxygen-regulated protein 1
- retinitis pigmentosa 1 protein
- retinitis pigmentosa RP1 protein homolog
- retinitis pigmentosa 1 homolog
Proteomics products related to RP1 Gene
Other products related to RP1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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