SET7 (SET Domain Containing 8 Pseudogene 1, SETD8P1)
Short Description: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.
More information related to gene SET7.
More information related to gene SET7.
Products related to SET7 Gene:
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4 results :
gRNA + Cas9
GEEN, PExp
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases, Protein Expression
- Gene:
- SET Domain Containing 8 Pseudogene 1 (SETD8P1)
- NCBI Accession:
- NG_003193
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA
GEEN, PExp
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Genome Editing with Engineered Nucleases, Protein Expression
- Gene:
- SET Domain Containing 8 Pseudogene 1 (SETD8P1)
- NCBI Accession:
- NG_003193
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
GEEN, PExp
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases, Protein Expression
- Gene:
- SET Domain Containing 8 Pseudogene 1 (SETD8P1)
- NCBI Accession:
- NG_003193
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA
GEEN, PExp
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Genome Editing with Engineered Nucleases, Protein Expression
- Gene:
- SET Domain Containing 8 Pseudogene 1 (SETD8P1)
- NCBI Accession:
- NG_003193
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
Synonyms and alternative names related to SET7
- SET domain containing lysine methyltransferase 7 (SETD7)
- SET domain containing (lysine methyltransferase) 7 (Setd7)
- 1600028F23Rik
- H3K4MT
- KMT7
- mKIAA1717
- SET7
- Set7
- SET7/9
- Set7/9
- SET9
Gene-IDs for different species
Protein level used designations for SET7
- H3-K4-HMTase SETD7
- SET domain-containing protein 7
- histone H3-K4 methyltransferase SETD7
- histone H3-lysine 4-specific methyltransferase
- histone-lysine N-methyltransferase SETD7
- lysine N-methyltransferase 7
- H3-K4 methyltransferase
Proteomics products related to SET7 Gene
Other products related to SET7 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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