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SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7, SIGLEC7)

Short Description: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).
More information related to gene SIGLEC7.

Products related to SIGLEC7 Gene:

30 results :

Human SIGLEC7 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7)
NCBI Accession:
NM_016543
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5237967
Datasheet
Catalog No. ABIN5237967
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7)
NCBI Accession:
NM_016543
Species:
Human
Synonyms:
LOC468976, SIGLEC7
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of SIGLEC7
Format:
Viral Particles
Storage:
-80 °C
Human SIGLEC7 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7)
NCBI Accession:
NM_016543
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5122588
Datasheet
Catalog No. ABIN5122588
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7)
NCBI Accession:
NM_016543
Species:
Human
Synonyms:
LOC468976, SIGLEC7
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of SIGLEC7
Format:
Viral Particles
Storage:
-80 °C
Human SIGLEC7 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7)
NCBI Accession:
NM_016543
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4490298
Datasheet
Catalog No. ABIN4490298
Type:
cDNA
Application:
Protein Expression
Gene:
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7)
NCBI Accession:
NM_016543
Species:
Human
Synonyms:
LOC468976, SIGLEC7
Insert length:
1404 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human SIGLEC7 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7)
NCBI Accession:
NM_016543
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4840068
Datasheet
Catalog No. ABIN4840068
Type:
cDNA
Application:
Cloning
Gene:
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7)
NCBI Accession:
NM_016543
Species:
Human
Synonyms:
LOC468976, SIGLEC7
Insert length:
1404 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human SIGLEC7 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7)
NCBI Accession:
NM_016543
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4633767
Datasheet
Catalog No. ABIN4633767
Type:
cDNA
Application:
Cloning
Gene:
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7)
NCBI Accession:
NM_016543
Species:
Human
Synonyms:
LOC468976, SIGLEC7
Insert length:
1404 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human SIGLEC7 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7)
NCBI Accession:
NM_016543
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4425208
Datasheet
Catalog No. ABIN4425208
Type:
cDNA
Application:
Protein Expression
Gene:
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7)
NCBI Accession:
NM_016543
Species:
Human
Synonyms:
LOC468976, SIGLEC7
Insert length:
1404 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human SIGLEC7 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7)
NCBI Accession:
NM_016543
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4710937
Datasheet
Catalog No. ABIN4710937
Type:
cDNA
Application:
Cloning
Gene:
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7)
NCBI Accession:
NM_016543
Species:
Human
Synonyms:
LOC468976, SIGLEC7
Insert length:
1404 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human SIGLEC7 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7)
NCBI Accession:
NM_016543
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5237966
Datasheet
Catalog No. ABIN5237966
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7)
NCBI Accession:
NM_016543
Species:
Human
Synonyms:
LOC468976, SIGLEC7
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of SIGLEC7
Format:
Viral Particles
Storage:
-80 °C
Human SIGLEC7 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7)
NCBI Accession:
NM_016543
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5122587
Datasheet
Catalog No. ABIN5122587
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7)
NCBI Accession:
NM_016543
Species:
Human
Synonyms:
LOC468976, SIGLEC7
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of SIGLEC7
Format:
Viral Particles
Storage:
-80 °C
Human SIGLEC7 ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7)
NCBI Accession:
NM_016543
Gene ID:
27036 (Human, SIGLEC7)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4923722
Datasheet
Catalog No. ABIN4923722
Type:
ORF
Application:
Protein Expression
Gene:
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7)
NCBI Accession:
NM_016543
Gene ID:
27036 (Human, SIGLEC7)
Synonyms:
LOC468976, SIGLEC7
Insert length:
1125 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Sequencing Primer:
    • Forward primer: 5'-TAATACGACTCACTATAGGG-3'
    • Reverse primer: 5'-CCTCGACTGTGCCTTCTA-3'
Components:
The GenEZ ORF clone is delivered as 10 μg of lyophilized plasmid DNA in a vial.
Format:
Lyophilized
Storage:
RT/-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
  • Reactivity
    • Human
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
  • Vector Backbone
    • pCMV6-Entry
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
  • Insert
    • ORF
    • cDNA
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • Enhanced CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Viral Particles
    • Liquid

Synonyms and alternative names related to SIGLEC7

  • sialic acid-binding Ig-like lectin 7 (LOC468976)
  • sialic acid binding Ig like lectin 7 (SIGLEC7)
  • AIRM1
  • CD328
  • CDw328
  • D-siglec
  • p75
  • p75/AIRM1
  • QA79
  • SIGLEC-7
  • SIGLEC7
  • SIGLEC19P
  • SIGLECP2

Gene-IDs for different species

Protein level used designations for SIGLEC7

  • sialic acid binding Ig-like lectin 7
  • AIRM-1
  • QA79 membrane protein
  • adhesion inhibitory receptor molecule 1, siglec-7
  • sialic acid binding immunoglobulin-like lectin 7
  • sialic acid-binding Ig-like lectin 7
Other products related to SIGLEC7 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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