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SLC12A1 (Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1, SLC12A1)

Short Description: This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.[provided by RefSeq, May 2010].
More information related to gene SLC12A1.

Products related to SLC12A1 Gene:

72 results :

Human SLC12A1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5757779
Datasheet
Catalog No. ABIN5757779
Type:
ORF
Application:
Cloning
Gene:
Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1)
Species:
Human
Synonyms:
si:ch211-220f12.1, SLC12A1, Slc12a1
Insert length:
1293 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human SLC12A1 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA PExp Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN5773292
Datasheet
Catalog No. ABIN5773292
Type:
cDNA
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1)
Species:
Human
Synonyms:
si:ch211-220f12.1, SLC12A1, Slc12a1
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human SLC12A1 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA PExp Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN5773291
Datasheet
Catalog No. ABIN5773291
Type:
cDNA
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1)
Species:
Human
Synonyms:
si:ch211-220f12.1, SLC12A1, Slc12a1
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human SLC12A1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4481148
Datasheet
Catalog No. ABIN4481148
Type:
cDNA
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1)
Species:
Human
Synonyms:
si:ch211-220f12.1, SLC12A1, Slc12a1
Insert length:
1293 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat SLC12A1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1)
NCBI Accession:
NM_019134
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5267867
Datasheet
Catalog No. ABIN5267867
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1)
NCBI Accession:
NM_019134
Species:
Rat
Synonyms:
si:ch211-220f12.1, SLC12A1, Slc12a1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Slc12a1
Format:
Viral Particles
Storage:
-80 °C
Mouse SLC12A1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1)
NCBI Accession:
NM_183354
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5267865
Datasheet
Catalog No. ABIN5267865
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1)
NCBI Accession:
NM_183354
Species:
Mouse
Synonyms:
si:ch211-220f12.1, SLC12A1, Slc12a1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Slc12a1
Format:
Viral Particles
Storage:
-80 °C
Human SLC12A1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1)
NCBI Accession:
NM_000338
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5267863
Datasheet
Catalog No. ABIN5267863
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1)
NCBI Accession:
NM_000338
Species:
Human
Synonyms:
si:ch211-220f12.1, SLC12A1, Slc12a1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of SLC12A1
Format:
Viral Particles
Storage:
-80 °C
Rat SLC12A1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1)
NCBI Accession:
NM_019134
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5152307
Datasheet
Catalog No. ABIN5152307
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1)
NCBI Accession:
NM_019134
Species:
Rat
Synonyms:
si:ch211-220f12.1, SLC12A1, Slc12a1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Slc12a1
Format:
Viral Particles
Storage:
-80 °C
Mouse SLC12A1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1)
NCBI Accession:
NM_183354
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5152305
Datasheet
Catalog No. ABIN5152305
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1)
NCBI Accession:
NM_183354
Species:
Mouse
Synonyms:
si:ch211-220f12.1, SLC12A1, Slc12a1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Slc12a1
Format:
Viral Particles
Storage:
-80 °C
Human SLC12A1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1)
NCBI Accession:
NM_000338
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5152303
Datasheet
Catalog No. ABIN5152303
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1)
NCBI Accession:
NM_000338
Species:
Human
Synonyms:
si:ch211-220f12.1, SLC12A1, Slc12a1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of SLC12A1
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • His-GST
    • His-MBP
    • HA tag
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pPB-His-GST
    • pPB-His-MBP
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-XL5
    • pDONR223
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to SLC12A1

  • si:ch211-220f12.1 (si:ch211-220f12.1)
  • solute carrier family 12 member 1 (SLC12A1)
  • solute carrier family 12 member 1 (Slc12a1)
  • solute carrier family 12, member 1 (Slc12a1)
  • AI788571
  • BSC1
  • D630042G03Rik
  • DKFZp469A2020
  • mBSC1
  • NKCC2
  • Nkcc2
  • slc12a1
  • SLC12A1
  • urehr3

Gene-IDs for different species

Protein level used designations for SLC12A1

  • FERM domain-containing protein 4A
  • Na/K/Cl cotransporter
  • solute carrier family 12 (sodium/potassium/chloride transporters), member 1
  • solute carrier family 12 member 1-like
  • NKCC2A variant A
  • Na-K-2Cl cotransporter
  • bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2
  • kidney-specific Na-K-Cl symporter
  • solute carrier family 12 member 1
  • Solute carrier family 12 member 1 (bumetanide-sensitive sodium-[potassium]-chloride cotransporter)
  • Solute carrier family 12, member 1 (bumetanide-sensitive sodium-[potassium]-chloride cotransporter)
  • apical Na(2Cl)K cotransporter
  • solute carrier family 12, member 1
  • BSC1
  • bumetanide-sensitive cotransporter type 1
Other products related to SLC12A1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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