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SLC12A3 (Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3, SLC12A3)

Short Description: This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome, a disease similar to Bartter's syndrome, that is characterized by hypokalemic alkalosis combined with hypomagnesemia, low urinary calcium, and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
More information related to gene SLC12A3.

Products related to SLC12A3 Gene:

70 results :

Human SLC12A3 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4490316
Datasheet
Catalog No. ABIN4490316
Type:
cDNA
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
Species:
Human
Synonyms:
SLC12A3, slc12a3.2, Slc12a3
Insert length:
3090 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human SLC12A3 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5734795
Datasheet
Catalog No. ABIN5734795
Type:
ORF
Application:
Cloning
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
Species:
Human
Synonyms:
SLC12A3, slc12a3.2, Slc12a3
Insert length:
3090 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat SLC12A3 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
NCBI Accession:
NM_019345
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5107963
Datasheet
Catalog No. ABIN5107963
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
NCBI Accession:
NM_019345
Species:
Rat
Synonyms:
SLC12A3, slc12a3.2, Slc12a3
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Slc12a3
Format:
Viral Particles
Storage:
-80 °C
Mouse SLC12A3 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
NCBI Accession:
NM_001205311
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5107961
Datasheet
Catalog No. ABIN5107961
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
NCBI Accession:
NM_001205311
Species:
Mouse
Synonyms:
SLC12A3, slc12a3.2, Slc12a3
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Slc12a3
Format:
Viral Particles
Storage:
-80 °C
Human SLC12A3 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
NCBI Accession:
NM_000339
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5107959
Datasheet
Catalog No. ABIN5107959
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
NCBI Accession:
NM_000339
Species:
Human
Synonyms:
SLC12A3, slc12a3.2, Slc12a3
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of SLC12A3
Format:
Viral Particles
Storage:
-80 °C
Human SLC12A3 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA PExp Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN5772529
Datasheet
Catalog No. ABIN5772529
Type:
cDNA
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
Species:
Human
Synonyms:
SLC12A3, slc12a3.2, Slc12a3
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human SLC12A3 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA PExp Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN5772528
Datasheet
Catalog No. ABIN5772528
Type:
cDNA
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
Species:
Human
Synonyms:
SLC12A3, slc12a3.2, Slc12a3
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human SLC12A3 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4633785
Datasheet
Catalog No. ABIN4633785
Type:
cDNA
Application:
Cloning
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
Species:
Human
Synonyms:
SLC12A3, slc12a3.2, Slc12a3
Insert length:
3090 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human SLC12A3 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4425226
Datasheet
Catalog No. ABIN4425226
Type:
cDNA
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
Species:
Human
Synonyms:
SLC12A3, slc12a3.2, Slc12a3
Insert length:
3090 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse SLC12A3 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
NCBI Accession:
NM_019415
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5734797
Datasheet
Catalog No. ABIN5734797
Type:
ORF
Application:
Cloning
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
NCBI Accession:
NM_019415
Species:
Mouse
Synonyms:
SLC12A3, slc12a3.2, Slc12a3
Insert length:
3006 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to SLC12A3

  • solute carrier family 12 member 3 (SLC12A3)
  • solute carrier family 12 (sodium/chloride transporter), member 3 (slc12a3.2)
  • solute carrier family 12 member 3 (Slc12a3)
  • solute carrier family 12, member 3 (Slc12a3)
  • AI035291
  • DKFZp469N2315
  • NCC
  • NCCT
  • SLC12A3
  • slc12a3
  • TSC

Gene-IDs for different species

Protein level used designations for SLC12A3

  • solute carrier family 12 (sodium/chloride transporters), member 3
  • thiazide-sensitive sodium chloride cotransporter
  • solute carrier family 12 (sodium/chloride transporters), member 3, gene 2
  • solute carrier family 12 member 3-like
  • Na-Cl cotransporter
  • Na-Cl symporter
  • NaCl electroneutral thiazide-sensitive cotransporter
  • solute carrier family 12 member 3
  • thiazide-sensitive Na-Cl cotransporter
  • thiazide-sensitive sodium-chloride cotransporter
  • solute carrier family 12, member 3
  • sodium chloride cotransporter
Other products related to SLC12A3 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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