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SMAD2 (SMAD, Mothers Against DPP Homolog 2, SMAD2)

Short Description: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012].
More information related to gene SMAD2.

Products related to SMAD2 Gene:

77 results :

Human SMAD2 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
SMAD, Mothers Against DPP Homolog 2 (SMAD2)
NCBI Accession:
NM_005901
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5728119
Datasheet
Catalog No. ABIN5728119
Type:
ORF
Application:
Cloning
Gene:
SMAD, Mothers Against DPP Homolog 2 (SMAD2)
NCBI Accession:
NM_005901
Species:
Human
Synonyms:
SMAD2, SMAD2Z, smad2, smad2.S, Smad2
Insert length:
1404 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human SMAD2 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
SMAD, Mothers Against DPP Homolog 2 (SMAD2)
NCBI Accession:
NM_005901
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4490407
Datasheet
Catalog No. ABIN4490407
Type:
cDNA
Application:
Protein Expression
Gene:
SMAD, Mothers Against DPP Homolog 2 (SMAD2)
NCBI Accession:
NM_005901
Species:
Human
Synonyms:
SMAD2, SMAD2Z, smad2, smad2.S, Smad2
Insert length:
1404 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat SMAD2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SMAD, Mothers Against DPP Homolog 2 (SMAD2)
NCBI Accession:
NM_019191
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5095628
Datasheet
Catalog No. ABIN5095628
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SMAD, Mothers Against DPP Homolog 2 (SMAD2)
NCBI Accession:
NM_019191
Species:
Rat
Synonyms:
SMAD2, SMAD2Z, smad2, smad2.S, Smad2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Smad2
Format:
Viral Particles
Storage:
-80 °C
Mouse SMAD2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SMAD, Mothers Against DPP Homolog 2 (SMAD2)
NCBI Accession:
NM_010754
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5095626
Datasheet
Catalog No. ABIN5095626
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SMAD, Mothers Against DPP Homolog 2 (SMAD2)
NCBI Accession:
NM_010754
Species:
Mouse
Synonyms:
SMAD2, SMAD2Z, smad2, smad2.S, Smad2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Smad2
Format:
Viral Particles
Storage:
-80 °C
Human SMAD2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SMAD, Mothers Against DPP Homolog 2 (SMAD2)
NCBI Accession:
NM_001003652
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5095624
Datasheet
Catalog No. ABIN5095624
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SMAD, Mothers Against DPP Homolog 2 (SMAD2)
NCBI Accession:
NM_001003652
Species:
Human
Synonyms:
SMAD2, SMAD2Z, smad2, smad2.S, Smad2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of SMAD2
Format:
Viral Particles
Storage:
-80 °C
Human SMAD2 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
SMAD, Mothers Against DPP Homolog 2 (SMAD2)
NCBI Accession:
NM_005901
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4840522
Datasheet
Catalog No. ABIN4840522
Type:
cDNA
Application:
Cloning
Gene:
SMAD, Mothers Against DPP Homolog 2 (SMAD2)
NCBI Accession:
NM_005901
Species:
Human
Synonyms:
SMAD2, SMAD2Z, smad2, smad2.S, Smad2
Insert length:
1404 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human SMAD2 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
SMAD, Mothers Against DPP Homolog 2 (SMAD2)
NCBI Accession:
NM_005901
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4633876
Datasheet
Catalog No. ABIN4633876
Type:
cDNA
Application:
Cloning
Gene:
SMAD, Mothers Against DPP Homolog 2 (SMAD2)
NCBI Accession:
NM_005901
Species:
Human
Synonyms:
SMAD2, SMAD2Z, smad2, smad2.S, Smad2
Insert length:
1404 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human SMAD2 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
SMAD, Mothers Against DPP Homolog 2 (SMAD2)
NCBI Accession:
NM_005901
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4425317
Datasheet
Catalog No. ABIN4425317
Type:
cDNA
Application:
Protein Expression
Gene:
SMAD, Mothers Against DPP Homolog 2 (SMAD2)
NCBI Accession:
NM_005901
Species:
Human
Synonyms:
SMAD2, SMAD2Z, smad2, smad2.S, Smad2
Insert length:
1404 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human SMAD2 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
SMAD, Mothers Against DPP Homolog 2 (SMAD2)
NCBI Accession:
NM_005901
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4711391
Datasheet
Catalog No. ABIN4711391
Type:
cDNA
Application:
Cloning
Gene:
SMAD, Mothers Against DPP Homolog 2 (SMAD2)
NCBI Accession:
NM_005901
Species:
Human
Synonyms:
SMAD2, SMAD2Z, smad2, smad2.S, Smad2
Insert length:
1404 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse SMAD2 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
SMAD, Mothers Against DPP Homolog 2 (SMAD2)
NCBI Accession:
NM_010754
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5728120
Datasheet
Catalog No. ABIN5728120
Type:
ORF
Application:
Cloning
Gene:
SMAD, Mothers Against DPP Homolog 2 (SMAD2)
NCBI Accession:
NM_010754
Species:
Mouse
Synonyms:
SMAD2, SMAD2Z, smad2, smad2.S, Smad2
Insert length:
1404 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCas-Guide
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC
    • pCMV6-XL5
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to SMAD2

  • SMAD family member 2 (SMAD2)
  • SMAD family member 2-Z (SMAD2Z)
  • SMAD family member 2 (smad2)
  • SMAD family member 2 S homeolog (smad2.S)
  • SMAD family member 2 (Smad2)
  • 7120426M23Rik
  • fj43c06
  • hMAD-2
  • hmad-2
  • hSMAD2
  • hsmad2
  • JV18
  • jv18
  • JV18-1
  • jv18-1
  • MADH2
  • madh2
  • Madh2
  • MAD homolog 2
  • MADR2
  • madr2
  • Madr2
  • mMad2
  • Mothers against DPP homolog 2
  • smad-2
  • Smad-2
  • SMAD 2
  • Smad2
  • wu:fj43c06
  • Xmad2
  • XSmad2

Gene-IDs for different species

Protein level used designations for SMAD2

  • MAD homolog 2
  • SMAD, mothers against DPP homolog 2
  • Sma- and Mad-related protein 2
  • mother against DPP homolog 2
  • mothers against decapentaplegic homolog 2
  • SMAD 2
  • mothers against DPP homolog 2
  • mothers against decapentaplegic-like 2
  • MAD (mothers against decapentaplegic, Drosophila) homolog 2
  • SMA- and MAD-related protein 2
  • SMAD family member 2
  • Smad 2
  • mad-related protein 2
  • LOW QUALITY PROTEIN: mothers against decapentaplegic homolog 2
Other products related to SMAD2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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