Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@genomics-online.com

SMCR8 (Smith-Magenis Syndrome Chromosome Region, Candidate 8, SMCR8)

Short Description: Component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy. In the complex, C9orf72 and SMCR8 probably constitute the catalytic subunits that promote the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation. The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity. {ECO:0000250|UniProtKB:Q8TEV9}.
More information related to gene SMCR8.

Products related to SMCR8 Gene:

57 results :

Human SMCR8 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
NCBI Accession:
NM_144775
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5769869
Datasheet
Catalog No. ABIN5769869
Type:
ORF
Application:
Cloning
Gene:
Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
NCBI Accession:
NM_144775
Species:
Human
Synonyms:
SMCR8, Smcr8, smcr8b
Insert length:
2814 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat SMCR8 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
NCBI Accession:
NM_001191919
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5293189
Datasheet
Catalog No. ABIN5293189
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
NCBI Accession:
NM_001191919
Species:
Rat
Synonyms:
SMCR8, Smcr8, smcr8b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Smcr8
Format:
Viral Particles
Storage:
-80 °C
Mouse SMCR8 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
NCBI Accession:
NM_175491
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5293187
Datasheet
Catalog No. ABIN5293187
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
NCBI Accession:
NM_175491
Species:
Mouse
Synonyms:
SMCR8, Smcr8, smcr8b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Smcr8
Format:
Viral Particles
Storage:
-80 °C
Human SMCR8 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
NCBI Accession:
NM_144775
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5293185
Datasheet
Catalog No. ABIN5293185
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
NCBI Accession:
NM_144775
Species:
Human
Synonyms:
SMCR8, Smcr8, smcr8b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of SMCR8
Format:
Viral Particles
Storage:
-80 °C
Rat SMCR8 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
NCBI Accession:
NM_001191919
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5177588
Datasheet
Catalog No. ABIN5177588
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
NCBI Accession:
NM_001191919
Species:
Rat
Synonyms:
SMCR8, Smcr8, smcr8b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Smcr8
Format:
Viral Particles
Storage:
-80 °C
Mouse SMCR8 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
NCBI Accession:
NM_175491
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5177586
Datasheet
Catalog No. ABIN5177586
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
NCBI Accession:
NM_175491
Species:
Mouse
Synonyms:
SMCR8, Smcr8, smcr8b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Smcr8
Format:
Viral Particles
Storage:
-80 °C
Human SMCR8 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
NCBI Accession:
NM_144775
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5177584
Datasheet
Catalog No. ABIN5177584
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
NCBI Accession:
NM_144775
Species:
Human
Synonyms:
SMCR8, Smcr8, smcr8b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of SMCR8
Format:
Viral Particles
Storage:
-80 °C
Mouse SMCR8 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
NCBI Accession:
NM_175491
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5769870
Datasheet
Catalog No. ABIN5769870
Type:
ORF
Application:
Cloning
Gene:
Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
NCBI Accession:
NM_175491
Species:
Mouse
Synonyms:
SMCR8, Smcr8, smcr8b
Insert length:
2358 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse SMCR8 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
NCBI Accession:
NM_001085440
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5769871
Datasheet
Catalog No. ABIN5769871
Type:
ORF
Application:
Cloning
Gene:
Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
NCBI Accession:
NM_001085440
Species:
Mouse
Synonyms:
SMCR8, Smcr8, smcr8b
Insert length:
2808 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat SMCR8 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
NCBI Accession:
NM_001191919
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5769872
Datasheet
Catalog No. ABIN5769872
Type:
ORF
Application:
Cloning
Gene:
Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
NCBI Accession:
NM_001191919
Species:
Rat
Synonyms:
SMCR8, Smcr8, smcr8b
Insert length:
2808 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Mouse
    • Human
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • His tag
    • GFP tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-AC-GFP
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Liquid
    • Lyophilized
    • Viral Particles

Synonyms and alternative names related to SMCR8

  • Smith-Magenis syndrome chromosome region, candidate 8 (SMCR8)
  • Smith-Magenis syndrome chromosome region, candidate 8 homolog (human) (Smcr8)
  • Smith-Magenis syndrome chromosome region, candidate 8 (Smcr8)
  • Smith-Magenis syndrome chromosome region, candidate 8b (smcr8b)
  • 2310076G09Rik
  • AI642055
  • D030073L15Rik
  • RGD1564621
  • smcr8

Gene-IDs for different species

Protein level used designations for SMCR8

  • Smith-Magenis syndrome chromosomal region candidate gene 8 protein
  • Smith-Magenis syndrome chromosomal region candidate gene 8 protein homolog
  • Smith-Magenis syndrome chromosome region, candidate 8 homolog
  • Smith-Magenis syndrome chromosomal region candidate gene 8 protein homolog B
  • guanine nucleotide exchange protein smcr8b
  • smith-Magenis syndrome chromosomal region candidate gene 8-B protein homolog
Other products related to SMCR8 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
You are here:

antibodies-online

german

german (deutsch) antikoerper-online.de

english

english (english) antibodies-online.com

french

french (français) anticorps-enligne.fr

chinese

chinese (中文) antibodies-online.cn

genomics-online

english

english (english) genomics-online.com

Support