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SMG8 (Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor, SMG8)

Short Description: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity (By similarity).
More information related to gene SMG8.

Products related to SMG8 Gene:

34 results :

Human SMG8 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Smg-8 Homolog, Nonsense Mediated MRNA Decay Factor (C. Elegans) (SMG8)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5766580
Datasheet
Catalog No. ABIN5766580
Type:
ORF
Application:
Cloning
Gene:
Smg-8 Homolog, Nonsense Mediated MRNA Decay Factor (C. Elegans) (SMG8)
Species:
Human
Synonyms:
SMG8, Smg8, smg-8
Insert length:
1929 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human SMG8 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (C. Elegans) (SMG8)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4472944
Datasheet
Catalog No. ABIN4472944
Type:
cDNA
Application:
Protein Expression
Gene:
Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (C. Elegans) (SMG8)
Species:
Human
Synonyms:
SMG8, Smg8, smg-8
Insert length:
1929 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse SMG8 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smg-8 Homolog, Nonsense Mediated MRNA Decay Factor (C. Elegans) (SMG8)
NCBI Accession:
NM_024262
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5296501
Datasheet
Catalog No. ABIN5296501
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smg-8 Homolog, Nonsense Mediated MRNA Decay Factor (C. Elegans) (SMG8)
NCBI Accession:
NM_024262
Species:
Mouse
Synonyms:
SMG8, Smg8, smg-8
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of 1200011M11Rik
Format:
Viral Particles
Storage:
-80 °C
Human SMG8 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smg-8 Homolog, Nonsense Mediated MRNA Decay Factor (C. Elegans) (SMG8)
NCBI Accession:
NM_018149
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5285639
Datasheet
Catalog No. ABIN5285639
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smg-8 Homolog, Nonsense Mediated MRNA Decay Factor (C. Elegans) (SMG8)
NCBI Accession:
NM_018149
Species:
Human
Synonyms:
SMG8, Smg8, smg-8
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of C17orf71
Format:
Viral Particles
Storage:
-80 °C
Mouse SMG8 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (C. Elegans) (SMG8)
NCBI Accession:
NM_024262
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5180890
Datasheet
Catalog No. ABIN5180890
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (C. Elegans) (SMG8)
NCBI Accession:
NM_024262
Species:
Mouse
Synonyms:
SMG8, Smg8, smg-8
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of 1200011M11Rik
Format:
Viral Particles
Storage:
-80 °C
Human SMG8 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (C. Elegans) (SMG8)
NCBI Accession:
NM_018149
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5170046
Datasheet
Catalog No. ABIN5170046
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (C. Elegans) (SMG8)
NCBI Accession:
NM_018149
Species:
Human
Synonyms:
SMG8, Smg8, smg-8
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of C17orf71
Format:
Viral Particles
Storage:
-80 °C
Human SMG8 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (C. Elegans) (SMG8)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4759319
Datasheet
Catalog No. ABIN4759319
Type:
cDNA
Application:
Cloning
Gene:
Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (C. Elegans) (SMG8)
Species:
Human
Synonyms:
SMG8, Smg8, smg-8
Insert length:
1929 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human SMG8 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (C. Elegans) (SMG8)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4434039
Datasheet
Catalog No. ABIN4434039
Type:
cDNA
Application:
Protein Expression
Gene:
Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (C. Elegans) (SMG8)
Species:
Human
Synonyms:
SMG8, Smg8, smg-8
Insert length:
1929 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse SMG8 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Smg-8 Homolog, Nonsense Mediated MRNA Decay Factor (C. Elegans) (SMG8)
NCBI Accession:
NM_024262
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5766579
Datasheet
Catalog No. ABIN5766579
Type:
ORF
Application:
Cloning
Gene:
Smg-8 Homolog, Nonsense Mediated MRNA Decay Factor (C. Elegans) (SMG8)
NCBI Accession:
NM_024262
Species:
Mouse
Synonyms:
SMG8, Smg8, smg-8
Insert length:
2976 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse SMG8 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smg-8 Homolog, Nonsense Mediated MRNA Decay Factor (C. Elegans) (SMG8)
NCBI Accession:
NM_024262
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5296500
Datasheet
Catalog No. ABIN5296500
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Smg-8 Homolog, Nonsense Mediated MRNA Decay Factor (C. Elegans) (SMG8)
NCBI Accession:
NM_024262
Species:
Mouse
Synonyms:
SMG8, Smg8, smg-8
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of 1200011M11Rik
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • DYKDDDDK Tag
    • His-GST
    • His-MBP
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pDONR223
    • pPB-His-GST
    • pPB-His-MBP
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Spectinomycin
    • Chloramphenicol
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to SMG8

  • SMG8, nonsense mediated mRNA decay factor (SMG8)
  • smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans) (Smg8)
  • Protein smg-8 (smg-8)
  • 1200011M11Rik
  • C17orf71
  • C19H17orf71

Gene-IDs for different species

Protein level used designations for SMG8

  • amplified in breast cancer gene 2 protein
  • protein SMG8
  • protein smg-8 homolog
  • smg-8 homolog, nonsense mediated mRNA decay factor
  • CG6729 gene product
Other products related to SMG8 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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