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SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal, SMPD1)

Short Description: The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010].
More information related to gene SMPD1.

Products related to SMPD1 Gene:

60 results :

Human SMPD1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5755024
Datasheet
Catalog No. ABIN5755024
Type:
ORF
Application:
Cloning
Gene:
Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1)
Species:
Human
Synonyms:
SMPD1, Smpd1, LOC5578088
Insert length:
1095 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse SMPD1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1)
NCBI Accession:
NM_011421
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5755025
Datasheet
Catalog No. ABIN5755025
Type:
ORF
Application:
Cloning
Gene:
Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1)
NCBI Accession:
NM_011421
Species:
Mouse
Synonyms:
SMPD1, Smpd1, LOC5578088
Insert length:
1884 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human SMPD1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4481397
Datasheet
Catalog No. ABIN4481397
Type:
cDNA
Application:
Protein Expression
Gene:
Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1)
Species:
Human
Synonyms:
SMPD1, Smpd1, LOC5578088
Insert length:
1095 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse SMPD1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1)
NCBI Accession:
NM_011421
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4456734
Datasheet
Catalog No. ABIN4456734
Type:
cDNA
Application:
Protein Expression
Gene:
Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1)
NCBI Accession:
NM_011421
Species:
Mouse
Synonyms:
SMPD1, Smpd1, LOC5578088
Insert length:
1884 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse SMPD1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1)
NCBI Accession:
NM_011421
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5262641
Datasheet
Catalog No. ABIN5262641
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1)
NCBI Accession:
NM_011421
Species:
Mouse
Synonyms:
SMPD1, Smpd1, LOC5578088
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Smpd1
Format:
Viral Particles
Storage:
-80 °C
Rat SMPD1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1)
NCBI Accession:
NM_001006997
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5262643
Datasheet
Catalog No. ABIN5262643
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1)
NCBI Accession:
NM_001006997
Species:
Rat
Synonyms:
SMPD1, Smpd1, LOC5578088
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Smpd1
Format:
Viral Particles
Storage:
-80 °C
Human SMPD1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1)
NCBI Accession:
NM_001007593
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5262639
Datasheet
Catalog No. ABIN5262639
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1)
NCBI Accession:
NM_001007593
Species:
Human
Synonyms:
SMPD1, Smpd1, LOC5578088
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of SMPD1
Format:
Viral Particles
Storage:
-80 °C
Rat SMPD1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1)
NCBI Accession:
NM_001006997
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5147122
Datasheet
Catalog No. ABIN5147122
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1)
NCBI Accession:
NM_001006997
Species:
Rat
Synonyms:
SMPD1, Smpd1, LOC5578088
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Smpd1
Format:
Viral Particles
Storage:
-80 °C
Mouse SMPD1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1)
NCBI Accession:
NM_011421
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5147120
Datasheet
Catalog No. ABIN5147120
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1)
NCBI Accession:
NM_011421
Species:
Mouse
Synonyms:
SMPD1, Smpd1, LOC5578088
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Smpd1
Format:
Viral Particles
Storage:
-80 °C
Human SMPD1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1)
NCBI Accession:
NM_001007593
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5147118
Datasheet
Catalog No. ABIN5147118
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1)
NCBI Accession:
NM_001007593
Species:
Human
Synonyms:
SMPD1, Smpd1, LOC5578088
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of SMPD1
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pCMV6-XL5
    • pDONR223
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to SMPD1

  • sphingomyelin phosphodiesterase 1 (SMPD1)
  • sphingomyelin phosphodiesterase 1, acid lysosomal (Smpd1)
  • sphingomyelin phosphodiesterase (LOC5578088)
  • sphingomyelin phosphodiesterase 1 (Smpd1)
  • sphingomyelin phosphodiesterase 1, acid lysosomal (SMPD1)
  • A-SMase
  • ASM
  • ASMASE
  • aSMase
  • NPD
  • SMPD1
  • Zn-SMase

Gene-IDs for different species

Protein level used designations for SMPD1

  • acid sphingomyelinase
  • sphingomyelin phosphodiesterase
  • sphingomyelin phosphodiesterase 1, acid lysosomal (acid sphingomyelinase)
  • aSMase
  • sphingomyelin phosphodiesterase 1, acid lysosomal
  • sphingomyelin phosphodiesterase 1
  • sphingomyelin phosphodiesterase-like
Other products related to SMPD1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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