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SOCS1 (Suppressor of Cytokine Signaling 1, SOCS1)

Short Description: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008].
More information related to gene SOCS1.

Products related to SOCS1 Gene:

53 results :

Mouse SOCS1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Suppressor of Cytokine Signaling 1 (SOCS1)
NCBI Accession:
NM_009896
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5097938
Datasheet
Catalog No. ABIN5097938
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Suppressor of Cytokine Signaling 1 (SOCS1)
NCBI Accession:
NM_009896
Species:
Mouse
Synonyms:
socs1a, socs1, SOCS1, socs1.L, Socs1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Socs1
Format:
Viral Particles
Storage:
-80 °C
Human SOCS1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Suppressor of Cytokine Signaling 1 (SOCS1)
NCBI Accession:
NM_003745
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5097936
Datasheet
Catalog No. ABIN5097936
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Suppressor of Cytokine Signaling 1 (SOCS1)
NCBI Accession:
NM_003745
Species:
Human
Synonyms:
socs1a, socs1, SOCS1, socs1.L, Socs1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of SOCS1
Format:
Viral Particles
Storage:
-80 °C
Mouse SOCS1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Suppressor of Cytokine Signaling 1 (SOCS1)
NCBI Accession:
NM_009896
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5729346
Datasheet
Catalog No. ABIN5729346
Type:
ORF
Application:
Cloning
Gene:
Suppressor of Cytokine Signaling 1 (SOCS1)
NCBI Accession:
NM_009896
Species:
Mouse
Synonyms:
socs1a, socs1, SOCS1, socs1.L, Socs1
Insert length:
639 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat SOCS1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Suppressor of Cytokine Signaling 1 (SOCS1)
NCBI Accession:
NM_145879
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5729347
Datasheet
Catalog No. ABIN5729347
Type:
ORF
Application:
Cloning
Gene:
Suppressor of Cytokine Signaling 1 (SOCS1)
NCBI Accession:
NM_145879
Species:
Rat
Synonyms:
socs1a, socs1, SOCS1, socs1.L, Socs1
Insert length:
639 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse SOCS1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Suppressor of Cytokine Signaling 1 (SOCS1)
NCBI Accession:
NM_009896
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5213176
Datasheet
Catalog No. ABIN5213176
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Suppressor of Cytokine Signaling 1 (SOCS1)
NCBI Accession:
NM_009896
Species:
Mouse
Synonyms:
socs1a, socs1, SOCS1, socs1.L, Socs1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Socs1
Format:
Viral Particles
Storage:
-80 °C
Human SOCS1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Suppressor of Cytokine Signaling 1 (SOCS1)
NCBI Accession:
NM_003745
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5213174
Datasheet
Catalog No. ABIN5213174
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Suppressor of Cytokine Signaling 1 (SOCS1)
NCBI Accession:
NM_003745
Species:
Human
Synonyms:
socs1a, socs1, SOCS1, socs1.L, Socs1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of SOCS1
Format:
Viral Particles
Storage:
-80 °C
Human SOCS1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Suppressor of Cytokine Signaling 1 (SOCS1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN5772367
Datasheet
Catalog No. ABIN5772367
Type:
cDNA
Application:
Protein Expression
Gene:
Suppressor of Cytokine Signaling 1 (SOCS1)
Species:
Human
Synonyms:
socs1a, socs1, SOCS1, socs1.L, Socs1
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat SOCS1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Suppressor of Cytokine Signaling 1 (SOCS1)
NCBI Accession:
NM_145879
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4464214
Datasheet
Catalog No. ABIN4464214
Type:
cDNA
Application:
Protein Expression
Gene:
Suppressor of Cytokine Signaling 1 (SOCS1)
NCBI Accession:
NM_145879
Species:
Rat
Synonyms:
socs1a, socs1, SOCS1, socs1.L, Socs1
Insert length:
774 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse SOCS1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Suppressor of Cytokine Signaling 1 (SOCS1)
NCBI Accession:
NM_009896
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4456872
Datasheet
Catalog No. ABIN4456872
Type:
cDNA
Application:
Protein Expression
Gene:
Suppressor of Cytokine Signaling 1 (SOCS1)
NCBI Accession:
NM_009896
Species:
Mouse
Synonyms:
socs1a, socs1, SOCS1, socs1.L, Socs1
Insert length:
639 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human SOCS1 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA PExp Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Suppressor of Cytokine Signaling 1 (SOCS1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN5772366
Datasheet
Catalog No. ABIN5772366
Type:
cDNA
Application:
Protein Expression
Gene:
Suppressor of Cytokine Signaling 1 (SOCS1)
Species:
Human
Synonyms:
socs1a, socs1, SOCS1, socs1.L, Socs1
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pORF
    • pRFP-C-RS
    • pCMV6-AC-GFP
    • pCMV6-XL4
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • shRNA
    • ORF
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to SOCS1

  • suppressor of cytokine signaling 1a (socs1a)
  • suppressor of cytokine signaling 1 (socs1)
  • suppressor of cytokine signaling 1 (SOCS1)
  • suppressor of cytokine signaling 1 L homeolog (socs1.L)
  • suppressor of cytokine signaling 1 (Socs1)
  • cis1
  • CIS1
  • cish1
  • CISH1
  • Cish1
  • Cish7
  • jab
  • JAB
  • LOC100228306
  • socs-1
  • SOCS-1
  • Socs-1
  • socs1
  • SOCS1
  • socs1b
  • ssi-1
  • SSI-1
  • ssi1
  • SSI1
  • tip3
  • TIP3
  • zgc:91868

Gene-IDs for different species

Protein level used designations for SOCS1

  • suppressor of cytokine signaling 1
  • suppressor of cytokine signalling
  • suppressor of cytokine signaling 1b
  • suppressor of cytokine signaling 1-like protein
  • JAK binding protein
  • JAK-binding protein
  • STAT induced SH3 protein 1
  • STAT-induced STAT inhibitor 1
  • TIP-3
  • Tec-interacting protein 3
  • cytokine-inducible SH2 protein 1
  • JAK2-binding protein
  • cytokine inducible SH2-containing protein 1
  • cytokine inducible SH2-containing protein 7
Other products related to SOCS1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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