SOCS2 (Suppressor of Cytokine Signaling 2, SOCS2)
Short Description: This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012].
More information related to gene SOCS2.
More information related to gene SOCS2.
Products related to SOCS2 Gene:
Recommended next Filters:
78 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Suppressor of Cytokine Signaling 2 (SOCS2)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Suppressor of Cytokine Signaling 2 (SOCS2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Suppressor of Cytokine Signaling 2 (SOCS2)
- NCBI Accession:
- NM_058208
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Suppressor of Cytokine Signaling 2 (SOCS2)
- NCBI Accession:
- NM_007706
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Suppressor of Cytokine Signaling 2 (SOCS2)
- NCBI Accession:
- NM_003877
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Suppressor of Cytokine Signaling 2 (SOCS2)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Suppressor of Cytokine Signaling 2 (SOCS2)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-N-His
Kanamycin
T7 Promoter
His tag
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Suppressor of Cytokine Signaling 2 (SOCS2)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-N-His
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His tag
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-His
Kanamycin
CMV Promoter
His tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Suppressor of Cytokine Signaling 2 (SOCS2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-His
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- His tag
- Expression:
- Stable, Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Suppressor of Cytokine Signaling 2 (SOCS2)
- NCBI Accession:
- NM_001168656
- Species:
- Mouse
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
Synonyms and alternative names related to SOCS2
- suppressor of cytokine signaling 2 (SOCS2)
- suppressor of cytokine signaling 1 (Socs1)
- suppressor of cytokine signaling 2 (Socs2)
- suppressor of cytokine signaling 2 (socs2)
- death domain-containing protein CRADD (LOC100716104)
- suppressor of cytokine signaling 2 S homeolog (socs2.S)
- 8030460M17
- AI527257
- AW108012
- CIS2
- cis2
- Cish1
- Cish2
- cish2
- Cradd
- D130043N08Rik
- hg
- JAB
- si:dkey-202b22.1
- Socs-1
- SOCS-2
- Socs-2
- socs-2
- socs2
- Socs2
- SSI-2
- ssi-2
- SSI2
- ssi2
- STATI2
- stati2
Gene-IDs for different species
Protein level used designations for SOCS2
- CIS-2
- STAT induced STAT inhibitor-2
- STAT-induced STAT inhibitor 2
- STAT-induced STAT inhibitor-2
- cytokine-inducible SH2 protein 2
- suppressor of cytokine signaling-2
- cytokine inducible SH2-containing protein 1
- cytokine inducible SH2-containing protein 2
- SOCS-2
- suppressor of cytokine signalling 2
- suppressor of cytokine signaling 2
- suppressor of cytokine signaling 2 variant 1
- CASP2 and RIPK1 domain containing adaptor with death domain
- death domain-containing protein CRADD
- suppressor of cytokine signaling 2 S homeolog
Proteomics products related to SOCS2 Gene
Other products related to SOCS2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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