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SPTLC3 (Serine Palmitoyltransferase, Long Chain Base Subunit 3, SPTLC3)

Short Description: The SPTLC3 gene encodes an isoform of the third subunit of serine palmitoyltransferase (SPT\; EC 2.3.1.50), which catalyzes the rate-limiting step of the de novo synthesis of sphingolipids (Hornemann et al., 2006 [PubMed 17023427]). SPT contains 2 main subunits: the common SPTLC1 subunit (MIM 605712) and either SPTLC2 (MIM 605713) or its isoform SPTLC2L (SPTLC3), depending on the tissue in which biosynthesis occurs (Hornemann et al., 2006 [PubMed 17023427]). There are also 2 highly related isoforms of a third subunit, SSSPTA (MIM 613540) and SSSPTB (MIM 610412), that confer acyl-CoA preference of the SPT enzyme and are essential for maximal enzyme activity (Han et al., 2009 [PubMed 19416851]).[supplied by OMIM, Nov 2010].
More information related to gene SPTLC3.

Products related to SPTLC3 Gene:

59 results :

Human SPTLC3 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5736877
Datasheet
Catalog No. ABIN5736877
Type:
ORF
Application:
Cloning
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
Species:
Human
Synonyms:
SPTLC3, sptlc3.S, LOC100438231, sptlc3, LOC100546896, Sptlc3
Insert length:
528 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human SPTLC3 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4481593
Datasheet
Catalog No. ABIN4481593
Type:
cDNA
Application:
Protein Expression
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
Species:
Human
Synonyms:
SPTLC3, sptlc3.S, LOC100438231, sptlc3, LOC100546896, Sptlc3
Insert length:
528 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse SPTLC3 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
NCBI Accession:
NM_175467
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5111860
Datasheet
Catalog No. ABIN5111860
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
NCBI Accession:
NM_175467
Species:
Mouse
Synonyms:
SPTLC3, sptlc3.S, LOC100438231, sptlc3, LOC100546896, Sptlc3
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Sptlc3
Format:
Viral Particles
Storage:
-80 °C
Rat SPTLC3 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
NCBI Accession:
NM_001106517
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5111862
Datasheet
Catalog No. ABIN5111862
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
NCBI Accession:
NM_001106517
Species:
Rat
Synonyms:
SPTLC3, sptlc3.S, LOC100438231, sptlc3, LOC100546896, Sptlc3
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Sptlc3
Format:
Viral Particles
Storage:
-80 °C
Human SPTLC3 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
NCBI Accession:
NM_018327
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5111858
Datasheet
Catalog No. ABIN5111858
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
NCBI Accession:
NM_018327
Species:
Human
Synonyms:
SPTLC3, sptlc3.S, LOC100438231, sptlc3, LOC100546896, Sptlc3
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of SPTLC3
Format:
Viral Particles
Storage:
-80 °C
Human SPTLC3 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4840897
Datasheet
Catalog No. ABIN4840897
Type:
cDNA
Application:
Cloning
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
Species:
Human
Synonyms:
SPTLC3, sptlc3.S, LOC100438231, sptlc3, LOC100546896, Sptlc3
Insert length:
528 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human SPTLC3 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4711766
Datasheet
Catalog No. ABIN4711766
Type:
cDNA
Application:
Cloning
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
Species:
Human
Synonyms:
SPTLC3, sptlc3.S, LOC100438231, sptlc3, LOC100546896, Sptlc3
Insert length:
528 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human SPTLC3 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4625064
Datasheet
Catalog No. ABIN4625064
Type:
cDNA
Application:
Cloning
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
Species:
Human
Synonyms:
SPTLC3, sptlc3.S, LOC100438231, sptlc3, LOC100546896, Sptlc3
Insert length:
528 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human SPTLC3 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4416507
Datasheet
Catalog No. ABIN4416507
Type:
cDNA
Application:
Protein Expression
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
Species:
Human
Synonyms:
SPTLC3, sptlc3.S, LOC100438231, sptlc3, LOC100546896, Sptlc3
Insert length:
528 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse SPTLC3 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
NCBI Accession:
NM_175467
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5736878
Datasheet
Catalog No. ABIN5736878
Type:
ORF
Application:
Cloning
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
NCBI Accession:
NM_175467
Species:
Mouse
Synonyms:
SPTLC3, sptlc3.S, LOC100438231, sptlc3, LOC100546896, Sptlc3
Insert length:
1692 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pDONR223
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to SPTLC3

  • serine palmitoyltransferase long chain base subunit 3 (SPTLC3)
  • serine palmitoyltransferase, long chain base subunit 3 S homeolog (sptlc3.S)
  • serine palmitoyltransferase 3 (LOC100438231)
  • serine palmitoyltransferase, long chain base subunit 3 (sptlc3)
  • serine palmitoyltransferase 3 (LOC100546896)
  • serine palmitoyltransferase long chain base subunit 3 (sptlc3)
  • serine palmitoyltransferase, long chain base subunit 3 (Sptlc3)
  • C20orf38
  • C130053K05Rik
  • dJ718P11
  • dJ718P11.1
  • hLCB2b
  • LCB2B
  • LCB3
  • MGC130979
  • RGD1310030
  • SPT3
  • SPTLC2L

Gene-IDs for different species

Protein level used designations for SPTLC3

  • serine palmitoyltransferase, long chain base subunit 3
  • serine palmitoyltransferase, long chain base subunit 2-like (aminotransferase 2)
  • serine palmitoyltransferase 3-like
  • serine palmitoyltransferase 3
  • LCB 3
  • SPT 3
  • long chain base biosynthesis protein 2b
  • long chain base biosynthesis protein 3
  • serine-palmitoyl-CoA transferase 3
  • LCB2b
Other products related to SPTLC3 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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