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TAB1 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1, TAB1)

Short Description: The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
More information related to gene TAB1.

Products related to TAB1 Gene:

62 results :

Human TAB1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5752230
Datasheet
Catalog No. ABIN5752230
Type:
ORF
Application:
Cloning
Gene:
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1)
Species:
Human
Synonyms:
TAB1, Tab1
Insert length:
1515 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human TAB1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4477847
Datasheet
Catalog No. ABIN4477847
Type:
cDNA
Application:
Protein Expression
Gene:
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1)
Species:
Human
Synonyms:
TAB1, Tab1
Insert length:
1515 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat TAB1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1)
NCBI Accession:
NM_001109976
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5256895
Datasheet
Catalog No. ABIN5256895
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1)
NCBI Accession:
NM_001109976
Species:
Rat
Synonyms:
TAB1, Tab1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Tab1
Format:
Viral Particles
Storage:
-80 °C
Mouse TAB1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1)
NCBI Accession:
NM_025609
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5256893
Datasheet
Catalog No. ABIN5256893
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1)
NCBI Accession:
NM_025609
Species:
Mouse
Synonyms:
TAB1, Tab1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Tab1
Format:
Viral Particles
Storage:
-80 °C
Human TAB1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1)
NCBI Accession:
NM_006116
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5256891
Datasheet
Catalog No. ABIN5256891
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1)
NCBI Accession:
NM_006116
Species:
Human
Synonyms:
TAB1, Tab1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of TAB1
Format:
Viral Particles
Storage:
-80 °C
Human TAB1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1)
NCBI Accession:
NM_153497
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5256889
Datasheet
Catalog No. ABIN5256889
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1)
NCBI Accession:
NM_153497
Species:
Human
Synonyms:
TAB1, Tab1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of MAP3K7IP1
Format:
Viral Particles
Storage:
-80 °C
Human TAB1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1)
NCBI Accession:
NM_006116
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5141392
Datasheet
Catalog No. ABIN5141392
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1)
NCBI Accession:
NM_006116
Species:
Human
Synonyms:
TAB1, Tab1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of TAB1
Format:
Viral Particles
Storage:
-80 °C
Rat TAB1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1)
NCBI Accession:
NM_001109976
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5141396
Datasheet
Catalog No. ABIN5141396
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1)
NCBI Accession:
NM_001109976
Species:
Rat
Synonyms:
TAB1, Tab1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Tab1
Format:
Viral Particles
Storage:
-80 °C
Mouse TAB1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1)
NCBI Accession:
NM_025609
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5141394
Datasheet
Catalog No. ABIN5141394
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1)
NCBI Accession:
NM_025609
Species:
Mouse
Synonyms:
TAB1, Tab1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Tab1
Format:
Viral Particles
Storage:
-80 °C
Human TAB1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1)
NCBI Accession:
NM_153497
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5141390
Datasheet
Catalog No. ABIN5141390
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1)
NCBI Accession:
NM_153497
Species:
Human
Synonyms:
TAB1, Tab1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of MAP3K7IP1
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • DYKDDDDK Tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pPB-His-GST
    • pPB-His-MBP
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC
    • pCMV6-XL6
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • PGK Promoter
    • SFFV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • SP6 Promoter
  • Format
    • Lyophilized
    • Viral Particles
    • Liquid

Synonyms and alternative names related to TAB1

  • TGF-beta activated kinase 1 (MAP3K7) binding protein 1 (TAB1)
  • TGF-beta activated kinase 1/MAP3K7 binding protein 1 (Tab1)
  • 3'-Tab1
  • 2310012M03Rik
  • b2b449Clo
  • MAP3K7IP1
  • Map3k7ip1

Gene-IDs for different species

Protein level used designations for TAB1

  • TAK1-binding protein 1
  • TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
  • mitogen-activated protein kinase kinase kinase 7-interacting protein 1
  • transforming growth factor beta-activated kinase-binding protein 1
  • TGF-beta-activated kinase 1-binding protein 1
  • Tak1-binding protein 1
  • beta activated kinase-1 binding protein-1
  • mitogen activated protein kinase kinase kinase 7 interacting protein 1
  • mitogen-activated protein kinase kinase kinase 7 interacting protein 1
Other products related to TAB1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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