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TPMT (Thiopurine S-Methyltransferase, TPMT)

Short Description: This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q. [provided by RefSeq, Jul 2008].
More information related to gene TPMT.

Products related to TPMT Gene:

64 results :

Human TPMT ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Thiopurine S-Methyltransferase (TPMT)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5742715
Datasheet
Catalog No. ABIN5742715
Type:
ORF
Application:
Cloning
Gene:
Thiopurine S-Methyltransferase (TPMT)
Species:
Human
Synonyms:
tpmt.L, tpmt.2, tpmT, MCA0794, Pnap_4948, Hhal_1383, TK90_1044, Slit_1144, Tint_0842, Fbal_3334, Celly_3188, Weevi_1737, Psefu_2696, Metme_3860, Tpmt, TPMT
Insert length:
738 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human TPMT ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Thiopurine S-Methyltransferase (TPMT)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5742716
Datasheet
Catalog No. ABIN5742716
Type:
ORF
Application:
Cloning
Gene:
Thiopurine S-Methyltransferase (TPMT)
Species:
Human
Synonyms:
tpmt.L, tpmt.2, tpmT, MCA0794, Pnap_4948, Hhal_1383, TK90_1044, Slit_1144, Tint_0842, Fbal_3334, Celly_3188, Weevi_1737, Psefu_2696, Metme_3860, Tpmt, TPMT
Insert length:
738 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human TPMT cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Thiopurine S-Methyltransferase (TPMT)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4482475
Datasheet
Catalog No. ABIN4482475
Type:
cDNA
Application:
Protein Expression
Gene:
Thiopurine S-Methyltransferase (TPMT)
Species:
Human
Synonyms:
tpmt.L, tpmt.2, tpmT, MCA0794, Pnap_4948, Hhal_1383, TK90_1044, Slit_1144, Tint_0842, Fbal_3334, Celly_3188, Weevi_1737, Psefu_2696, Metme_3860, Tpmt, TPMT
Insert length:
738 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human TPMT cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Thiopurine S-Methyltransferase (TPMT)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4482474
Datasheet
Catalog No. ABIN4482474
Type:
cDNA
Application:
Protein Expression
Gene:
Thiopurine S-Methyltransferase (TPMT)
Species:
Human
Synonyms:
tpmt.L, tpmt.2, tpmT, MCA0794, Pnap_4948, Hhal_1383, TK90_1044, Slit_1144, Tint_0842, Fbal_3334, Celly_3188, Weevi_1737, Psefu_2696, Metme_3860, Tpmt, TPMT
Insert length:
738 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse TPMT CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Thiopurine S-Methyltransferase (TPMT)
NCBI Accession:
NM_016785
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5238403
Datasheet
Catalog No. ABIN5238403
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Thiopurine S-Methyltransferase (TPMT)
NCBI Accession:
NM_016785
Species:
Mouse
Synonyms:
tpmt.L, tpmt.2, tpmT, MCA0794, Pnap_4948, Hhal_1383, TK90_1044, Slit_1144, Tint_0842, Fbal_3334, Celly_3188, Weevi_1737, Psefu_2696, Metme_3860, Tpmt, TPMT
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Tpmt
Format:
Viral Particles
Storage:
-80 °C
Human TPMT CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Thiopurine S-Methyltransferase (TPMT)
NCBI Accession:
NM_000367
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5238401
Datasheet
Catalog No. ABIN5238401
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Thiopurine S-Methyltransferase (TPMT)
NCBI Accession:
NM_000367
Species:
Human
Synonyms:
tpmt.L, tpmt.2, tpmT, MCA0794, Pnap_4948, Hhal_1383, TK90_1044, Slit_1144, Tint_0842, Fbal_3334, Celly_3188, Weevi_1737, Psefu_2696, Metme_3860, Tpmt, TPMT
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of TPMT
Format:
Viral Particles
Storage:
-80 °C
Rat TPMT CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Thiopurine S-Methyltransferase (TPMT)
NCBI Accession:
NM_001079531
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5238405
Datasheet
Catalog No. ABIN5238405
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Thiopurine S-Methyltransferase (TPMT)
NCBI Accession:
NM_001079531
Species:
Rat
Synonyms:
tpmt.L, tpmt.2, tpmT, MCA0794, Pnap_4948, Hhal_1383, TK90_1044, Slit_1144, Tint_0842, Fbal_3334, Celly_3188, Weevi_1737, Psefu_2696, Metme_3860, Tpmt, TPMT
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Tpmt
Format:
Viral Particles
Storage:
-80 °C
Human TPMT CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Thiopurine S-Methyltransferase (TPMT)
NCBI Accession:
NM_000367
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5123012
Datasheet
Catalog No. ABIN5123012
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Thiopurine S-Methyltransferase (TPMT)
NCBI Accession:
NM_000367
Species:
Human
Synonyms:
tpmt.L, tpmt.2, tpmT, MCA0794, Pnap_4948, Hhal_1383, TK90_1044, Slit_1144, Tint_0842, Fbal_3334, Celly_3188, Weevi_1737, Psefu_2696, Metme_3860, Tpmt, TPMT
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of TPMT
Format:
Viral Particles
Storage:
-80 °C
Rat TPMT CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Thiopurine S-Methyltransferase (TPMT)
NCBI Accession:
NM_001079531
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5123016
Datasheet
Catalog No. ABIN5123016
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Thiopurine S-Methyltransferase (TPMT)
NCBI Accession:
NM_001079531
Species:
Rat
Synonyms:
tpmt.L, tpmt.2, tpmT, MCA0794, Pnap_4948, Hhal_1383, TK90_1044, Slit_1144, Tint_0842, Fbal_3334, Celly_3188, Weevi_1737, Psefu_2696, Metme_3860, Tpmt, TPMT
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Tpmt
Format:
Viral Particles
Storage:
-80 °C
Mouse TPMT CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Thiopurine S-Methyltransferase (TPMT)
NCBI Accession:
NM_016785
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5123014
Datasheet
Catalog No. ABIN5123014
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Thiopurine S-Methyltransferase (TPMT)
NCBI Accession:
NM_016785
Species:
Mouse
Synonyms:
tpmt.L, tpmt.2, tpmT, MCA0794, Pnap_4948, Hhal_1383, TK90_1044, Slit_1144, Tint_0842, Fbal_3334, Celly_3188, Weevi_1737, Psefu_2696, Metme_3860, Tpmt, TPMT
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Tpmt
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • ProteoGenix
    • GenScript
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCas-Guide
    • pDONR223
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to TPMT

  • thiopurine S-methyltransferase L homeolog (tpmt.L)
  • thiopurine S-methyltransferase, tandem duplicate 2 (tpmt.2)
  • thiopurine S-methyltransferase TpmT (tpmT)
  • thiopurine S-methyltransferase (MCA0794)
  • thiopurine S-methyltransferase (Pnap_4948)
  • thiopurine S-methyltransferase (Hhal_1383)
  • thiopurine S-methyltransferase (TK90_1044)
  • thiopurine S-methyltransferase (Slit_1144)
  • thiopurine S-methyltransferase (Tint_0842)
  • Thiopurine S-methyltransferase (Fbal_3334)
  • thiopurine S-methyltransferase (Celly_3188)
  • thiopurine S-methyltransferase (Weevi_1737)
  • Thiopurine S-methyltransferase (Psefu_2696)
  • Thiopurine S-methyltransferase (Metme_3860)
  • thiopurine methyltransferase (Tpmt)
  • thiopurine S-methyltransferase (TPMT)
  • thiopurine S-methyltransferase (Tpmt)
  • AW106912
  • MGC84277
  • NHLRC1

Gene-IDs for different species

Protein level used designations for TPMT

  • thiopurine S-methyltransferase
  • Thiopurine S-methyltransferase
  • S-adenosyl-L-methionine:thiopurine S-methyltransferase
  • thiopurine methyltransferase
  • NHL repeat containing 1
Other products related to TPMT such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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