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TWEAK (Tumor Necrosis Factor (Ligand) Superfamily, Member 12, TNFSF12)

Short Description: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene\; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010].
More information related to gene TWEAK.

Products related to TWEAK Gene:

76 results :

Human TNFSF12 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5751700
Datasheet
Catalog No. ABIN5751700
Type:
ORF
Application:
Cloning
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12)
Species:
Human
Synonyms:
TNFSF12, Tnfsf12
Insert length:
405 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human TNFSF12 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5751701
Datasheet
Catalog No. ABIN5751701
Type:
ORF
Application:
Cloning
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12)
Species:
Human
Synonyms:
TNFSF12, Tnfsf12
Insert length:
750 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human TNFSF12 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4482400
Datasheet
Catalog No. ABIN4482400
Type:
cDNA
Application:
Protein Expression
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12)
Species:
Human
Synonyms:
TNFSF12, Tnfsf12
Insert length:
405 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human TNFSF12 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4486353
Datasheet
Catalog No. ABIN4486353
Type:
cDNA
Application:
Protein Expression
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12)
Species:
Human
Synonyms:
TNFSF12, Tnfsf12
Insert length:
750 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat TNFSF12 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12)
NCBI Accession:
NM_001001513
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5255909
Datasheet
Catalog No. ABIN5255909
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12)
NCBI Accession:
NM_001001513
Species:
Rat
Synonyms:
TNFSF12, Tnfsf12
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Tnfsf12
Format:
Viral Particles
Storage:
-80 °C
Mouse TNFSF12 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12)
NCBI Accession:
NM_011614
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5255907
Datasheet
Catalog No. ABIN5255907
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12)
NCBI Accession:
NM_011614
Species:
Mouse
Synonyms:
TNFSF12, Tnfsf12
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Tnfsf12
Format:
Viral Particles
Storage:
-80 °C
Human TNFSF12 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12)
NCBI Accession:
NM_003809
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5255905
Datasheet
Catalog No. ABIN5255905
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12)
NCBI Accession:
NM_003809
Species:
Human
Synonyms:
TNFSF12, Tnfsf12
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of TNFSF12
Format:
Viral Particles
Storage:
-80 °C
Rat TNFSF12 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12)
NCBI Accession:
NM_001001513
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5140412
Datasheet
Catalog No. ABIN5140412
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12)
NCBI Accession:
NM_001001513
Species:
Rat
Synonyms:
TNFSF12, Tnfsf12
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Tnfsf12
Format:
Viral Particles
Storage:
-80 °C
Mouse TNFSF12 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12)
NCBI Accession:
NM_011614
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5140410
Datasheet
Catalog No. ABIN5140410
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12)
NCBI Accession:
NM_011614
Species:
Mouse
Synonyms:
TNFSF12, Tnfsf12
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Tnfsf12
Format:
Viral Particles
Storage:
-80 °C
Human TNFSF12 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12)
NCBI Accession:
NM_003809
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5140408
Datasheet
Catalog No. ABIN5140408
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12)
NCBI Accession:
NM_003809
Species:
Human
Synonyms:
TNFSF12, Tnfsf12
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of TNFSF12
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • ProteoGenix
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-V-RS
    • pGFP-C-shLenti
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pDONR223
    • pRFP-C-RS
    • pCMV6-AC-GFP
    • pCMV6-XL4
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to TWEAK

  • TNF superfamily member 12 (TNFSF12)
  • tumor necrosis factor (ligand) superfamily, member 12 (TNFSF12)
  • tumor necrosis factor (ligand) superfamily, member 12 (Tnfsf12)
  • TNF superfamily member 12 (Tnfsf12)
  • APO3L
  • Apo3l
  • Dr3l
  • DR3LG
  • Dr3lg
  • TWEAK
  • Tweak

Gene-IDs for different species

Protein level used designations for TWEAK

  • APO3 ligand
  • APO3/DR3 ligand
  • TNF-related WEAK inducer of apoptosis
  • tumor necrosis factor ligand superfamily member 12
  • tumor necrosis factor superfamily member 12
  • TNF-related weak inducer of apoptosis
Other products related to TWEAK such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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