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ube3a (Ubiquitin Protein Ligase E3A, ube3a)

Short Description: This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul 2008].
More information related to gene ube3a.

Products related to ube3a Gene:

76 results :

Human ube3a ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Ubiquitin Protein Ligase E3A (ube3a)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5730557
Datasheet
Catalog No. ABIN5730557
Type:
ORF
Application:
Cloning
Gene:
Ubiquitin Protein Ligase E3A (ube3a)
Species:
Human
Synonyms:
UBE3A, ube3a, LOC100194730, Ube3a, ube3a.S, Eint_040430
Insert length:
1758 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human ube3a cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Ubiquitin Protein Ligase E3A (ube3a)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4482835
Datasheet
Catalog No. ABIN4482835
Type:
cDNA
Application:
Protein Expression
Gene:
Ubiquitin Protein Ligase E3A (ube3a)
Species:
Human
Synonyms:
UBE3A, ube3a, LOC100194730, Ube3a, ube3a.S, Eint_040430
Insert length:
1758 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat ube3a CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Protein Ligase E3A (ube3a)
NCBI Accession:
NM_001191837
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5100107
Datasheet
Catalog No. ABIN5100107
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Protein Ligase E3A (ube3a)
NCBI Accession:
NM_001191837
Species:
Rat
Synonyms:
UBE3A, ube3a, LOC100194730, Ube3a, ube3a.S, Eint_040430
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ube3a
Format:
Viral Particles
Storage:
-80 °C
Mouse ube3a CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Protein Ligase E3A (ube3a)
NCBI Accession:
NM_173010
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5100105
Datasheet
Catalog No. ABIN5100105
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Protein Ligase E3A (ube3a)
NCBI Accession:
NM_173010
Species:
Mouse
Synonyms:
UBE3A, ube3a, LOC100194730, Ube3a, ube3a.S, Eint_040430
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ube3a
Format:
Viral Particles
Storage:
-80 °C
Human ube3a CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Protein Ligase E3A (ube3a)
NCBI Accession:
NM_130839
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5100103
Datasheet
Catalog No. ABIN5100103
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Protein Ligase E3A (ube3a)
NCBI Accession:
NM_130839
Species:
Human
Synonyms:
UBE3A, ube3a, LOC100194730, Ube3a, ube3a.S, Eint_040430
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of UBE3A
Format:
Viral Particles
Storage:
-80 °C
Human ube3a CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Protein Ligase E3A (ube3a)
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5100101
Datasheet
Catalog No. ABIN5100101
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Protein Ligase E3A (ube3a)
Species:
Human
Synonyms:
UBE3A, ube3a, LOC100194730, Ube3a, ube3a.S, Eint_040430
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ANCR
Format:
Viral Particles
Storage:
-80 °C
Human ube3a cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Ubiquitin Protein Ligase E3A (ube3a)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4842771
Datasheet
Catalog No. ABIN4842771
Type:
cDNA
Application:
Cloning
Gene:
Ubiquitin Protein Ligase E3A (ube3a)
Species:
Human
Synonyms:
UBE3A, ube3a, LOC100194730, Ube3a, ube3a.S, Eint_040430
Insert length:
1758 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human ube3a cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Ubiquitin Protein Ligase E3A (ube3a)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4626306
Datasheet
Catalog No. ABIN4626306
Type:
cDNA
Application:
Cloning
Gene:
Ubiquitin Protein Ligase E3A (ube3a)
Species:
Human
Synonyms:
UBE3A, ube3a, LOC100194730, Ube3a, ube3a.S, Eint_040430
Insert length:
1758 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human ube3a cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Ubiquitin Protein Ligase E3A (ube3a)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4713640
Datasheet
Catalog No. ABIN4713640
Type:
cDNA
Application:
Cloning
Gene:
Ubiquitin Protein Ligase E3A (ube3a)
Species:
Human
Synonyms:
UBE3A, ube3a, LOC100194730, Ube3a, ube3a.S, Eint_040430
Insert length:
1758 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human ube3a cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Ubiquitin Protein Ligase E3A (ube3a)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4417749
Datasheet
Catalog No. ABIN4417749
Type:
cDNA
Application:
Protein Expression
Gene:
Ubiquitin Protein Ligase E3A (ube3a)
Species:
Human
Synonyms:
UBE3A, ube3a, LOC100194730, Ube3a, ube3a.S, Eint_040430
Insert length:
1758 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pDONR223
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Cloning Vector
    • Retroviral Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • gRNA + Cas9
    • gRNA
    • shRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to ube3a

  • ubiquitin protein ligase E3A (UBE3A)
  • ubiquitin-protein ligase E3A (ube3a)
  • ubiquitin-protein ligase E3A (LOC100194730)
  • ubiquitin protein ligase E3A (Ube3a)
  • ubiquitin protein ligase E3A (ube3a)
  • Ubiquitin protein ligase E3A (Ube3a)
  • ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) S homeolog (ube3a.S)
  • ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) (ube3a)
  • ubiquitin protein ligase E3A (Eint_040430)
  • 4732496B02
  • 5830462N02Rik
  • A130086L21Rik
  • ANCR
  • AS
  • As
  • CG6190
  • das
  • DDBDRAFT_0188760
  • DDBDRAFT_0302447
  • DDB_0188760
  • DDB_0302447
  • Dmel\\CG6190
  • Dube3a
  • dUBE3A
  • dube3A
  • dube3a
  • E6-AP
  • EPVE6AP
  • HPVE6A
  • Hpve6a
  • im:7140733
  • MGC69536
  • mKIAA4216
  • ube3a
  • UBE3A
  • UME3A
  • zgc:92173

Gene-IDs for different species

Protein level used designations for ube3a

  • CTCL tumor antigen se37-2
  • E6AP ubiquitin-protein ligase
  • human papilloma virus E6-associated protein
  • human papillomavirus E6-associated protein
  • oncogenic protein-associated protein E6-AP
  • renal carcinoma antigen NY-REN-54
  • ubiquitin-protein ligase E3A
  • ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome)
  • ubiquitin protein ligase E3A
  • E6-AP ubiquitin protein ligase
  • ubiquitin conjugating enzyme E3A
  • CG6190-PA
  • Ube3a-PA
  • drosophila angelman syndrome
  • angelman syndrome
  • ubiquitin-protein ligase E3A-like
Other products related to ube3a such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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