UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1, UGT1A1)
Short Description: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome. [provided by RefSeq, Jul 2008].
More information related to gene UGT1A1.
More information related to gene UGT1A1.
Products related to UGT1A1 Gene:
Recommended next Filters:
62 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1)
- NCBI Accession:
- NM_201645
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1)
- NCBI Accession:
- NM_000463
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1)
- NCBI Accession:
- NM_012683
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1)
- NCBI Accession:
- NM_201645
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1)
- NCBI Accession:
- NM_000463
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1)
- NCBI Accession:
- NM_012683
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
Synonyms and alternative names related to UGT1A1
- UDP glucuronosyltransferase family 1 member A1 (UGT1A1)
- UDP glucuronosyltransferase 1 family, polypeptide A1 (Ugt1a1)
- UDP glucuronosyltransferase 1 family, polypeptide A1 (UGT1A1)
- UDP-glucuronosyltransferase 1-1 (LOC100065342)
- UDP-glucuronosyltransferase (LOC100125517)
- UDP-glucuronosyltransferase 1-1 (LOC100229734)
- UDP-glucuronosyltransferase 1-6 (LOC100405984)
- UDP-glucuronosyltransferase 1-1 (LOC100511479)
- UDP glucuronosyltransferase family 1 member A1 (Ugt1a1)
- UDP glucuronosyltransferase 1 family polypeptide a1 (ugt1a1)
- BILIQTL1
- GNT1
- Gnt1
- HUG-BR1
- UDPGT
- Udpgt
- Udpgt-1a
- UDPGT 1-1
- UGT1
- Ugt1
- UGT1A
- UGT1A01
- UgtBr1
- zgc:123097
Gene-IDs for different species
Protein level used designations for UGT1A1
- UDP glycosyltransferase 1 family, polypeptide A1
- UDP-glucuronosyltransferase 1-1
- UDP-glucuronosyltransferase 1-A
- UDP-glucuronosyltransferase 1A1
- UGT-1A
- UGT1*1
- UGT1-01
- UGT1.1
- bilirubin UDP-glucuronosyltransferase 1-1
- bilirubin UDP-glucuronosyltransferase isozyme 1
- bilirubin-specific UDPGT isozyme 1
- UDP-glucuronosyltransferase 1 family, member 1
- UDP-glucuronosyltransferase 1 family, polypeptide A1
- UDPGT
- UDP glucuronosyltransferase 1 family, polypeptide A1
- uridine diphosphate glucuronosyltransferase 1A1
- UDP-glucuronosyltransferase UGT1A01
- UDP glucuronosyltransferase 1 family polypeptide A1
- UDP glycosyl transferase 1A1
- UDP-glucuronosyltransferase 1-1-like
- B1
- UDP-glucuronosyltransferase 1 family member 1
Proteomics products related to UGT1A1 Gene
Other products related to UGT1A1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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