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USP13 (Ubiquitin Specific Peptidase 13 (Isopeptidase T-3), USP13)

Short Description: Deubiquitinase that mediates deubiquitination of target proteins such as BECN1, MITF, SKP2 and USP10 and is involved in various processes such as autophagy and endoplasmic reticulum- associated degradation (ERAD). Component of a regulatory loop that of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. Also deubiquitinates USP10, an essential regulator of p53/TP53 stability. In turn, PIK3C3/VPS34- containing complexes regulate USP13 stability, suggesting the existence of a regulatory system by which PIK3C3/VPS34-containing complexes regulate p53/TP53 protein levels via USP10 and USP13. Recruited by nuclear UFD1 and mediates deubiquitination of SKP2, thereby regulating endoplasmic reticulum-associated degradation (ERAD). Mediates stabilization of SIAH2 independently of impairing SIAH2 autoubiquitination. Has a weak deubiquitinase activity in vitro and preferentially cleaves 'Lys-63'-linked polyubiquitin chains. In contrast to USP5, it is not able to mediate unanchored polyubiquitin disassembly. Able to cleave ISG15 in vitro\; however, additional experiments are required to confirm such data (By similarity).
More information related to gene USP13.

Products related to USP13 Gene:

57 results :

Human USP13 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4842928
Datasheet
Catalog No. ABIN4842928
Type:
cDNA
Application:
Cloning
Gene:
Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13)
Species:
Human
Synonyms:
USP13, Usp13, usp13, MGYG_01656, RR_RS02895
Insert length:
2592 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human USP13 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4713797
Datasheet
Catalog No. ABIN4713797
Type:
cDNA
Application:
Cloning
Gene:
Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13)
Species:
Human
Synonyms:
USP13, Usp13, usp13, MGYG_01656, RR_RS02895
Insert length:
2592 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human USP13 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5742877
Datasheet
Catalog No. ABIN5742877
Type:
ORF
Application:
Cloning
Gene:
Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13)
Species:
Human
Synonyms:
USP13, Usp13, usp13, MGYG_01656, RR_RS02895
Insert length:
2592 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat USP13 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13)
NCBI Accession:
NM_001107665
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5238679
Datasheet
Catalog No. ABIN5238679
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13)
NCBI Accession:
NM_001107665
Species:
Rat
Synonyms:
USP13, Usp13, usp13, MGYG_01656, RR_RS02895
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Usp13
Format:
Viral Particles
Storage:
-80 °C
Mouse USP13 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13)
NCBI Accession:
NM_001013024
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5238677
Datasheet
Catalog No. ABIN5238677
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13)
NCBI Accession:
NM_001013024
Species:
Mouse
Synonyms:
USP13, Usp13, usp13, MGYG_01656, RR_RS02895
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Usp13
Format:
Viral Particles
Storage:
-80 °C
Human USP13 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13)
NCBI Accession:
NM_003940
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5238675
Datasheet
Catalog No. ABIN5238675
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13)
NCBI Accession:
NM_003940
Species:
Human
Synonyms:
USP13, Usp13, usp13, MGYG_01656, RR_RS02895
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of USP13
Format:
Viral Particles
Storage:
-80 °C
Rat USP13 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13)
NCBI Accession:
NM_001107665
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5123286
Datasheet
Catalog No. ABIN5123286
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13)
NCBI Accession:
NM_001107665
Species:
Rat
Synonyms:
USP13, Usp13, usp13, MGYG_01656, RR_RS02895
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Usp13
Format:
Viral Particles
Storage:
-80 °C
Human USP13 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13)
NCBI Accession:
NM_003940
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5123282
Datasheet
Catalog No. ABIN5123282
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13)
NCBI Accession:
NM_003940
Species:
Human
Synonyms:
USP13, Usp13, usp13, MGYG_01656, RR_RS02895
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of USP13
Format:
Viral Particles
Storage:
-80 °C
Mouse USP13 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13)
NCBI Accession:
NM_001013024
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5123284
Datasheet
Catalog No. ABIN5123284
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13)
NCBI Accession:
NM_001013024
Species:
Mouse
Synonyms:
USP13, Usp13, usp13, MGYG_01656, RR_RS02895
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Usp13
Format:
Viral Particles
Storage:
-80 °C
Mouse USP13 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13)
NCBI Accession:
NM_001013024
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5742878
Datasheet
Catalog No. ABIN5742878
Type:
ORF
Application:
Cloning
Gene:
Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13)
NCBI Accession:
NM_001013024
Species:
Mouse
Synonyms:
USP13, Usp13, usp13, MGYG_01656, RR_RS02895
Insert length:
2577 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to USP13

  • ubiquitin specific peptidase 13 (USP13)
  • ubiquitin specific peptidase 13 (isopeptidase T-3) (Usp13)
  • ubiquitin specific peptidase 13 (isopeptidase T-3) (USP13)
  • ubiquitin specific peptidase 13 (usp13)
  • ubiquitin specific peptidase 13 (isopeptidase T-3) (usp13)
  • ubiquitin carboxyl-terminal hydrolase 13 (MGYG_01656)
  • universal stress protein (RR_RS02895)
  • 2700071E21Rik
  • AI848077
  • IsoT-3
  • ISOT3
  • MGC163140
  • usp13

Gene-IDs for different species

Protein level used designations for USP13

  • deubiquitinating enzyme 13
  • isopeptidase T-3
  • ubiquitin carboxyl-terminal hydrolase 13
  • ubiquitin specific protease 13 (isopeptidase T-3)
  • ubiquitin thioesterase 13
  • ubiquitin thiolesterase 13
  • ubiquitin-specific-processing protease 13
  • ubiquitin specific peptidase 13 (isopeptidase T-3)
  • ubiquitin carboxyl-terminal hydrolase 13-like
  • ubiquitin thiolesterase 13-like
  • Deubiquitinating enzyme 13
  • Ubiquitin thioesterase 13
  • Ubiquitin-specific-processing protease 13
  • ubiquitin specific peptidase 13
  • universal stress protein
Other products related to USP13 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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